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Table 5 Comparison of radiation-related toxicities of patients between SIB-IMRT and conventional IMRT

From: Comparison of efficacy and safety between simultaneous integrated boost intensity-modulated radiotherapy and conventional intensity-modulated radiotherapy in locally advanced non-small-cell lung cancer: a retrospective study

Adverse event SIB-IMRT (n = 128) Conventional IMRT (n = 298) P value
Grade 2 Grade 3 Grade 4 Grade 5 Grade 2 Grade 3 Grade 4 Grade 5
Pneumonitis 22 (17.2%) 3 (2.3%) 0 5 (3.9%) 45 (15.1%) 3 (1%) 0 5 (1.7%) 0.337
Esophagitis 32 (25%) 4 (3.1%) 0 0 70 (23.5%) 4 (1.3%) 0 0 0.448
Skin toxicity 8 (6.3%) 1 (0.8%) 0 0 25 (8.4%) 2 (0.7%) 0 0 0.738
Leukopenia 30 (23.4%) 15 (11.7%) 2 (1.6%) 0 62 (20.8%) 28 (9.4%) 6 (2%) 0 0.868
Thrombocytopenia 7 (5.5%) 3 (2.3%) 1 (0.8%) 0 6 (2.0%) 3 (1%) 1 (0.3%) 0 0.262
Anemia 12 (9.4%) 0 0 0 18 (6%) 0 0 0 0.234
Vomiting 3 (2.3%) 1 (0.8%) 0 0 18 (6%) 0 0 0 0.069