Skip to main content

Table 3 Comparison of radiation dose to OARs of patients between SIB-IMRT and conventional IMRT

From: Comparison of efficacy and safety between simultaneous integrated boost intensity-modulated radiotherapy and conventional intensity-modulated radiotherapy in locally advanced non-small-cell lung cancer: a retrospective study

variables SIB-IMRT Conventional IMRT P value
median (range) median (range)
Radiation dose (Gy) 59.92 (50–70) 60 (50–70) 0.627
Lung V5 (%) 60.98 (28.63–89.39) 52.29 (22.67–87.4) <0.001*
Lung V20 (%) 25.26 (12.89–29.76) 22.82 (5.96–30.58) <0.001*
Lung V30 (%) 17.7 (7.14–22.74) 17.35 (2.16–24.46) 0.113
Mean lung dose (Gy) 15.10 (7.11–18.81) 14.08 (6.72–18.96) 0.001*
Maximum esophageal dose (Gy) 63.28 (12.21–73.95) 64.86 (12.41–75.26) 0.021*
Mean esophageal dose (Gy) 26.78 (7.88–50.63) 25.91 (4.31–50.63) 0.202
Esophageal V40 (%) 36.75 (3.59–86.64) 35.47 (0–77.17) 0.063
Esophageal V50 (%) 26.28 (0.75–73.84) 28.25 (0–66.3) 0.571
Mean heart dose (Gy) 13.12 (8.53–31.62) 11.5 (29.6–31.69) 0.044*
Heart V30 (%) 15.51 (0.42–54.68) 12.92 (0–46.73) 0.025*
Heart V40 (%) 9.21 (0–31.48) 8.05 (0–29.86) 0.309
Maximum spinal cord dose (Gy) 38.44 (30.26–64.87) 37.77 (9.12–42.42) 0.002*
Maximum spinal cord PRV dose (Gy) 42.98 (4.43–68.44) 43.11 (9.97–50.49) 0..96
  1. V5 Volumes receiving more than 5Gy, V20 Volumes receiving more than 20Gy, V30 Volumes receiving more than 30Gy, V40 Volumes receiving more than 40Gy, V50 Volumes receiving more than 50Gy, PRV Planning organ at risk volume
  2. *p<0.05 was considered significant