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Table 2 The comparison of the organs at risk (OAR) dose using dosimetric parameters

From: Evaluation of optimal treatment planning for radiotherapy of synchronous bilateral breast cancer including regional lymph node irradiation

  Treatment plans    
VMAT only1) Primary hybrid plan2) Modified hybrid plan3)   p a   
Mean (SD) Mean (SD) Mean (SD) p value 1) vs 2) 1) vs 3) 2) vs 3)
Whole Lung
 Dmean (Gy) 14.4 (0.67) 11.8 (1.19) 11.6 (1.18) < 0.001 < 0.001 < 0.001 0.935
 V5Gy (%) 67.9 (9.63) 57.0 (6.34) 56.7 (6.38) < 0.001 0.001 0.001 0.993
 V10Gy (%) 41.1 (7.9) 33.2 (4.39) 34.0 (5.6) < 0.001 0.003 0.008 0.926
 V20Gy (%) 27.5 (2.02) 19.2 (2.42) 19.0 (2.4) < 0.001 < 0.001 < 0.001 0.971
Heart
 Dmean (Gy) 13.2 (2.33) 8.0 (2.61) 8.0 (2.6) < 0.001 < 0.001 < 0.001 1
 V25Gy (%) 11.5 (6.41) 4.0 (4.71) 4.0 (4.71) 0.001 0.001 0.001 1
 V30Gy (%) 6.4 (4.86) 2.4 (3.49) 2.4 (3.49) 0.005 0.024 0.023 1
LAD
 Dmean (Gy) 21.8 (3.73) 14.7 (5.25) 14.7 (5.27) < 0.001 0.001 0.001 0.999
 Dmax (Gy) 33.7 (2.65) 33.0 (7.19) 32.9 (7.15) 0.566 0.947 0.933 0.999
 V10Gy (%) 92.7 (12.88) 56.7 (23.19) 54.9 (23.61) < 0.001 < 0.001 < 0.001 0.97
 V20Gy (%) 59.8 (21.3) 29.2 (22.38) 29.0 (22.46) 0.001 0.001 0.001 1