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Table 2 The comparison of the organs at risk (OAR) dose using dosimetric parameters

From: Evaluation of optimal treatment planning for radiotherapy of synchronous bilateral breast cancer including regional lymph node irradiation

 

Treatment plans

   

VMAT only1)

Primary hybrid plan2)

Modified hybrid plan3)

 

p a

  

Mean

(SD)

Mean

(SD)

Mean

(SD)

p value

1) vs 2)

1) vs 3)

2) vs 3)

Whole Lung

 Dmean

(Gy)

14.4

(0.67)

11.8

(1.19)

11.6

(1.18)

< 0.001

< 0.001

< 0.001

0.935

 V5Gy

(%)

67.9

(9.63)

57.0

(6.34)

56.7

(6.38)

< 0.001

0.001

0.001

0.993

 V10Gy

(%)

41.1

(7.9)

33.2

(4.39)

34.0

(5.6)

< 0.001

0.003

0.008

0.926

 V20Gy

(%)

27.5

(2.02)

19.2

(2.42)

19.0

(2.4)

< 0.001

< 0.001

< 0.001

0.971

Heart

 Dmean

(Gy)

13.2

(2.33)

8.0

(2.61)

8.0

(2.6)

< 0.001

< 0.001

< 0.001

1

 V25Gy

(%)

11.5

(6.41)

4.0

(4.71)

4.0

(4.71)

0.001

0.001

0.001

1

 V30Gy

(%)

6.4

(4.86)

2.4

(3.49)

2.4

(3.49)

0.005

0.024

0.023

1

LAD

 Dmean

(Gy)

21.8

(3.73)

14.7

(5.25)

14.7

(5.27)

< 0.001

0.001

0.001

0.999

 Dmax

(Gy)

33.7

(2.65)

33.0

(7.19)

32.9

(7.15)

0.566

0.947

0.933

0.999

 V10Gy

(%)

92.7

(12.88)

56.7

(23.19)

54.9

(23.61)

< 0.001

< 0.001

< 0.001

0.97

 V20Gy

(%)

59.8

(21.3)

29.2

(22.38)

29.0

(22.46)

0.001

0.001

0.001

1