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Table 3 Dose parameters for the PTVbrain according to the four planning modalities

From: Dosimetric evaluation of four whole brain radiation therapy approaches with hippocampus and inner ear avoidance and simultaneous integrated boost for limited brain metastases

  sIMRT dIMRT VMAT Tomo p value
D2% (Gy) 39.1 ± 1.2 39.4 ± 1.1 40.6 ± 2.4 37.5 ± 2.8 e,f
D98% (Gy) 14.7 ± 3.2 14.9 ± 3.3 21.7 ± 1.1 25.2 ± 2.0 b,c,d,e,f
Dmedian (Gy) 32.1 ± 0.7 32.1 ± 0.6 33.2 ± 1.1 31.6 ± 0.4 b,d,f
TC (%) 88.2 ± 4.2 90.6 ± 1.8 88.7 ± 2.6 92.6 ± 2.1 p = 0.05
HI 0.76 ± 0.11 0.76 ± 0.12 0.57 ± 0.08 0.39 ± 0.11 b,c,d,e,f
CI 0.75 ± 0.04 0.77 ± 0.03 0.76 ± 0.03 0.79 ± 0.06 > 0.05
  1. Each value was calculated from the data for all 10 patients. Values are expressed as mean ± SD. sIMRT step-and-shoot intensity-modulated radiotherapy, dIMRT dynamic intensity-modulated radiation therapy, VMAT volumetric-modulated arc therapy, Tomo helical tomotherapy. a: sIMRT vs dIMRT, b: sIMRT vs VMAT, c: sIMRT vs Tomo, d: dIMRT vs VMAT, e: dIMRT vs Tomo, f: VMAT vs Tomo. If c is in the “p value” column, it means that there is statistical significance between sIMRT and Tomo