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Table 3 Dose parameters for the PTVbrain according to the four planning modalities

From: Dosimetric evaluation of four whole brain radiation therapy approaches with hippocampus and inner ear avoidance and simultaneous integrated boost for limited brain metastases

 

sIMRT

dIMRT

VMAT

Tomo

p value

D2% (Gy)

39.1 ± 1.2

39.4 ± 1.1

40.6 ± 2.4

37.5 ± 2.8

e,f

D98% (Gy)

14.7 ± 3.2

14.9 ± 3.3

21.7 ± 1.1

25.2 ± 2.0

b,c,d,e,f

Dmedian (Gy)

32.1 ± 0.7

32.1 ± 0.6

33.2 ± 1.1

31.6 ± 0.4

b,d,f

TC (%)

88.2 ± 4.2

90.6 ± 1.8

88.7 ± 2.6

92.6 ± 2.1

p = 0.05

HI

0.76 ± 0.11

0.76 ± 0.12

0.57 ± 0.08

0.39 ± 0.11

b,c,d,e,f

CI

0.75 ± 0.04

0.77 ± 0.03

0.76 ± 0.03

0.79 ± 0.06

> 0.05

  1. Each value was calculated from the data for all 10 patients. Values are expressed as mean ± SD. sIMRT step-and-shoot intensity-modulated radiotherapy, dIMRT dynamic intensity-modulated radiation therapy, VMAT volumetric-modulated arc therapy, Tomo helical tomotherapy. a: sIMRT vs dIMRT, b: sIMRT vs VMAT, c: sIMRT vs Tomo, d: dIMRT vs VMAT, e: dIMRT vs Tomo, f: VMAT vs Tomo. If c is in the “p value” column, it means that there is statistical significance between sIMRT and Tomo