Fig. 1
From: Strategy to avoid local recurrence in patients with locally advanced rectal cancer
As for the clinical target volume (CTV), the superior border did not go beyond the L5-S1 interspace, the lateral border did not go beyond the outer edge of the lesser pelvic cavity, and the posterior border did not go beyond the pelvic surface of the sacrum (a). TS-1 (80 mg/m2) was given orally after breakfast and dinner on days 1 to 5, days 8 to 12, days 22 to 26, and days 29 to 33. Irinotecan (60 mg/m2/day) was given as a continuous intravenous infusion over a 90-min period on days 1, 8, 22, and 29 (b)