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Table 1 Patients’ characteristics

From: Risk factors to identify patients who may not benefit from whole brain irradiation for brain metastases - a single institution analysis

Variable

Frequency

Median survival

Log Rank

Gender

  

N.S.

 Female

146

2.9 M

 

 Male

193

2.1 M

 

Age

  

p = 0.0002

 30–49

37

7.0 M

 

 50–69

184

2.5 M

 

 70–90

118

1.5 M

 

KPS

  

p = 0.0001

 90–100%

94

5.2 M

 

 70–80%

138

2.5 M

 

 < 70%

107

1.2 M

 

Time of occurrence

  

N.S.

 Synchronous with primary

130

2.8 M

 

 After primary

209

2.4 M

 

Hospitalization

  

p = 0.0001

 Yes

126

0.9 M

 

 No

213

3.5 M

 

Number of brain metastases

  

p = 0.031

 Singular/solitary

65

3.7 M

 

  ≤ 3

75

2.6 M

 

  > 3 or bulk

199

2.3 M

 

Primary disease status

  

p = 0.0244

 Controlled primary

64

3.8 M

 

 Uncontrolled primary

275

2.3 M

 

Tumor site (3 most common and other)

  

N.S.

 NSCLC

148

2.5 M

 

 SCLC

59

2.4 M

 

 Breast cancer

47

2.9 M

 

 Other

85

  
  1. Demographic data of the 339 patients with univariate analysis of potential risk factors for median survival. N.S. no significant difference