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Table 3 Odds ratio of coronary event over time

From: The relationship between radiation doses to coronary arteries and location of coronary stenosis requiring intervention in breast cancer survivors

 

Number of women

Number of events

Crude analysis

Adjusted modela

OR

95% CI

OR

95% CI

Proximal RCA

 0–4 years

27

7

2.31

(0.98–5.44)

2.22

(0.94–5.23)

 4–8 years

49

21

1.00

Ref.

1.00

Ref.

 8+ years

106

8

1.12

(0.41–3.10)

1.18

(0.42–3.29)

Mid RCA

 0–4 years

30

25

1.89

(0.91–3.94)

1.74

(0.83–3.64)

 4–8 years

50

10

1.00

Ref.

1.00

Ref.

 8+ years

102

9

0.91

(0.37–2.23)

1.00

(0.4–2.48)

Distal RCA

 0–4 years

15

9

2.42

(0.66–8.95)

2.03

(0.54–7.59)

 4–8 years

50

3

1.00

Ref.

1.00

Ref.

 8+ years

117

4

1.31

(0.29–5.84)

1.71

(0.38–7.82)

LMCA

 0–4 years

8

1

0.82

(0.05–13.1)

NA

 4–8 years

54

1

1.00

Ref.

 8+ years

120

3

2.94

(0.31–28.3)

Proximal LAD

 0–4 years

24

20

1.20

(0.60–2.42)

1.18

(0.58–2.38)

 4–8 years

55

13

1.00

Ref.

1.00

Ref.

 8+ years

103

11

0.89

(0.40–1.98)

0.93

(0.41–2.10)

Mid LAD

 0–4 years

30

24

1.30

(0.67–2.51)

1.23

(0.63–2.38)

 4–8 years

54

14

1.00

Ref.

1.00

Ref.

 8+ years

98

14

1.07

(0.51–2.25)

1.16

(0.55–2.46)

Distal LAD

 0–4 years

9

2

1.65

(0.15–18.2)

NA

 4–8 years

52

1

1.00

Ref.

 8+ years

121

4

3.93

(0.44–35.2)

Proximal LCX

 0–4 years

18

12

2.40

(0.77–7.45)

2.18

(0.70–6.78)

 4–8 years

49

4

1.00

Ref.

1.00

Ref.

 8+ years

115

12

3.08

(0.99–9.54)

4.12

(1.31–13.0)

Any segment

 0–4 years

79

78

1.21

(0.82–1.79)

1.10

(0.74–1.63)

 4–8 years

45

38

1.00

Ref.

1.00

Ref.

 8+ years

58

45

2.22

(1.44–3.43)

2.58

(1.65–4.01)

  1. Odds ratio of coronary event over time. RCA Right coronary artery, LMCA Left main coronary artery, LAD Left anterior descending artery, LCX Left circumflex artery, OR Odds ratio, CI Confidence interval, Ref. Reference, and NA Non applicable
  2. aAdjusted for age at breast cancer (BC) diagnosis, year of BC diagnosis, year of registration in the Swedish Coronary Angiography and Angioplasty Registry (SCAAR), endocrine therapy, chemotherapy, BMI, and smoking status