Skip to main content

Table 2 Sites of initial failure

From: Optimal timing and clinical value of radiotherapy in advanced ALK-rearranged non-small cell lung cancer with or without baseline brain metastases: implications from pattern of failure analyses

  All patients
(n = 52)
Patients with OF
(n = 26)
Patients with DF
(n = 12)
Patient with ODF
(n = 14)
n (%) n (%) n (%) n (%)
Initial PD
 Primary only 9 (17.3) 7 (26.9) 0 (0.0) 0 (0.0)
 Metastasis only 33 (63.5) 16 (61.5) 12 (100.0) 7 (50.0)
 Primary and metastasis 10 (19.2) 3 (11.5) 0 (0.0) 7 (50.0)
Site of initial failure
 Lung 17 (32.7) 7 (26.9) 2 (16.7) 8 (57.1)
 Liver 3 (5.8) 2 (7.7) 0 1 (7.1)
 Brain 31 (59.6) 15 (57.7) 6 (50.0) 10 (71.4)
 Bone 6 (11.5) 1 (3.8) 3 (25.0) 2 (14.3)
 Adrenal grand 1 (1.9) 0 (0.0) 0 1 (7.1)
 Regional LN 6 (11.5) 3 (11.5) 0 3 (21.4)
 Distant LN 4 (7.7) 2 (7.7) 0 2 (14.3)
 others 3 (5.8) 1 (3.8) 1 (8.3) 1 (7.1)
  1. OF original site failure, DF distant site failure, ODF simultaneous occurrence of OF and DF, n number, PD disease progression, LN lymph node