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Table 2 Treatment characteristics at first-line and second-line treatment, n = 75

From: Salvage radiotherapy for recurrent hypopharyngeal and laryngeal squamous cell carcinoma (SCC) after first-line treatment with surgery alone: a 10-year single-centre experience

first-line treatment (surgery)

number of previous surgeries

 1

46 (61)

 2

17 (23)

 3

10 (13)

 4

2 (3)

total laryngetomy

18 (24)

larynx-preserving surgery

57 (76)

 vocal cord tripping

2 (3)

 endoscopic laser resection

21 (28)

 partial laryngectomy

34 (45)

unilateral ND

10 (13)

bilateral ND

27 (36)

 ECS

11 (30)

second-line treatment (RT/CRT)

median EQD2 in Gy

67 Gy (60–72 Gy)

median PTV1

101 cc (21–1949 cc)

median PTV2

740 cc (51–72 cc)

concomitant chemotherapy

48 (64)

concomitant cetuximab

10 (13)

  1. abbreviations: RT radiotherapy, CRT chemoradiotherapy, ECS extracapsular spread, EQD2 equivalent dose in 2 Gy single dose fractions, ND neck dissection, PTV planning target volume