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Table 1 Patient characteristics and (in the last column) answers to the question about inclusion in the randomized QUARTZ study (number of participants who would have felt comfortable enrolling the patient)

From: Management of patients with brain metastases from non-small cell lung cancer and adverse prognostic features: multi-national radiation treatment recommendations are heterogeneous

Patient nr.

Age in years

NSCLC type

Primary tumor controlled

Other metastases

KPS

Largest lesion size [cm]

Lesion number (MRI)

Time int. [mo]a

Mol DS-GPA

DS-GPA

OS predb

QUARTZ incl.

1

69

squamous cell

yes

hep

50

3.8

3

10

1.0

0.5

2.3

2

2

60

poorly diff.

no

lym, adr, hep, ski

50

1.3

2

2

1.0

1.0

2.7

2

3

58

adeno NSCLC

no

hep, oss, oth

60

4.5

3

0

1.0

1.0

3.1

2

4

69

poorly diff.

no

hep, oss

60

2.1

1

8

1.0

1.0

2.6

2

5

61

poorly diff.

no

hep, adr, pul

60

3.3

7

10

0.5

0.0

2.6

2

6

64

squamous cell

no

pul, kidney

70

1.5

1

20

1.0

1.5

2,6

0

7

85

squamous cell

no

pul

60

1.8

1

18

0.5

1.0

< 2.0

2

8

66

adeno NSCLC

no

oss, adr, lym

60

1.0

7

0

0.5

0.0

2.8

1

9

65

poorly diff.

no

pul, oth

50

2.0

2

5

1.0

0.5

2.4

2

10

77

adeno NSCLC

yes

none

50

2.3

6

12

1.0

1.0

3.8

1

11

62

adeno NSCLC

yes

adr

70

2.1

5

29

0.5

0.5

4.1

1

12

78

adeno EGFR mut.

yes

oss

60

4.0

4

54

1.5

0.0

2.6

0

13

64

adeno NSCLC

yes

oss, adr, oth

50

1.4

7

3

0.5

0.0

3.4

2

14

68

adeno NSCLC

no

pul, pleura

60

2.2

3

8

1.0

0.5

2.6

1

15

66

squamous cell

yes

hep, adr, oss

70

1.5

18

8

0.5

0.5

3.0

3

16

65

adeno NSCLC

yes

pul

70

3.3

4

22

1.0

0.5

4.2

0

17

53

adeno NSCLC

no

hep, adr, oss

70

3.4

7

2

0.5

1.0

3.8

1

  1. NSCLC non-small cell lung cancer, EGFR epidermal growth factor receptor, hep liver, lym extrathoracic lymph nodes, adr adrenal gland, ski skin, oss bones, oth other organs, pul lung, KPS Karnofsky performance status, MRI magnetic resonance imaging scans, Mol DS-GPA molecular disease-specific graded prognostic assessment, OS pred nomogram-predicted median survival in months
  2. ainterval between lung cancer diagnosis and presentation with brain metastasis
  3. bpredicted survival per Barnholtz-Sloan nomogram [14]