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Table 8 Cisplatin treatment regimen and acute toxicity

From: 3-weekly or weekly cisplatin concurrently with radiotherapy for patients with squamous cell carcinoma of the head and neck – a multicentre, retrospective analysis

Toxicity

3-weekly

(n = 127)

Weekly

(n = 187)

Total

(n = 314)

p-value

Nephrotoxicity

0.016

 Yes

42 (33.1%)

39 (20.9%)

81 (25.8%)

 No

85 (66.9%)

148 (79.1%)

233 (74.2%)

Ototoxicity

0.711

 Yes

19 (15%)

24 (12.8%)

43 (13.7%)

 No

108 (85%)

163 (87.2%)

271 (86.3%)