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Table 4 Highest doses to Left Ventricle and Left Anterior Descending Artery according to low or high MHD among left-sided BC patients

From: Is mean heart dose a relevant surrogate parameter of left ventricle and coronary arteries exposure during breast cancer radiotherapy: a dosimetric evaluation based on individually-determined radiation dose (BACCARAT study)

Left-sided BC patients MHD ≤ 3Gy
N = 45
MHD > 3Gy
N = 44
Left Ventricle
 D2 (Gy): mean (range) 25.75 (4.49–55.48) 42.25 (21.30–53.17)
 patients with V40 > 0 30 (67%) 34 (77%)
 maximum value of V40 9.6% 20.0%
 patients with V50 > 0 3 (7%) 14 (32%)
 maximum value of V50 6.6% 7.0%
Left Anterior Descending Artery
 D2 (Gy): mean (range) 31.99 (2.19–56.42) 44.08 (18.60–53.32)
 patients with V40 > 0 25 (56%) 33 (75%)
 maximum value of V40 51.6% 59.5%
 patients with V50 > 0 3 (7%) 8 (18%)
 maximum value of V50 24.1% 50.7%
  1. MHD mean heart dose, D2 minimal dose received by the most irradiated 2% of the structure volume, V40 (in %) is the relative volume exposed to at least 40 Gy