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Table 4 Highest doses to Left Ventricle and Left Anterior Descending Artery according to low or high MHD among left-sided BC patients

From: Is mean heart dose a relevant surrogate parameter of left ventricle and coronary arteries exposure during breast cancer radiotherapy: a dosimetric evaluation based on individually-determined radiation dose (BACCARAT study)

Left-sided BC patients

MHD ≤ 3Gy

N = 45

MHD > 3Gy

N = 44

Left Ventricle

 D2 (Gy): mean (range)

25.75 (4.49–55.48)

42.25 (21.30–53.17)

 patients with V40 > 0

30 (67%)

34 (77%)

 maximum value of V40

9.6%

20.0%

 patients with V50 > 0

3 (7%)

14 (32%)

 maximum value of V50

6.6%

7.0%

Left Anterior Descending Artery

 D2 (Gy): mean (range)

31.99 (2.19–56.42)

44.08 (18.60–53.32)

 patients with V40 > 0

25 (56%)

33 (75%)

 maximum value of V40

51.6%

59.5%

 patients with V50 > 0

3 (7%)

8 (18%)

 maximum value of V50

24.1%

50.7%

  1. MHD mean heart dose, D2 minimal dose received by the most irradiated 2% of the structure volume, V40 (in %) is the relative volume exposed to at least 40 Gy