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Table 2 Dosimetric parameters for heart and cardiac substructures including coronary arteries

From: Is mean heart dose a relevant surrogate parameter of left ventricle and coronary arteries exposure during breast cancer radiotherapy: a dosimetric evaluation based on individually-determined radiation dose (BACCARAT study)

  Left-sided BC patients
N = 89
Right-sided BC patients
N = 15
Mean ± SD Range Mean ± SD Range
Heart
 MHD (Gy) 2.95 ± 1.49 0.87–6.72 0.46 ± 0.12 0.25–0.67
 D2 (Gy) 26.80 ± 17.40 3.95–48.87 2.16 ± 0.90 1.11–3.57
 Individual ratio D2/MHD 8.4 ± 3.6 2.9–15.4 4.6 ± 0.6 3.6–5.8
Left Ventricle
 Dmean (Gy) 6.25 ± 3.53 1.16–13.42 0.09 ± 0.04 0.04–0.17
 D2 (Gy) 34.01 ± 16.93 4.49–55.48 0.34 ± 0.13 0.17–0.54
 Individual ratio D2/Dmean 5.7 ± 2.0 2.6–11.0 3.9 ± 0.7 2.6–5.3
Left Anterior Descending Artery
 Dmean (Gy) 15.68 ± 8.13 1.68–37.61 0.37 ± 0.15 0.13–0.54
 D2 (Gy) 37.97 ± 15.93 2.19–56.42 0.45 ± 0.17 0.19–0.61
 Individual ratio D2/Dmean 2.6 ± 0.9 1.3–6.0 2.3 ± 0.6 1.3–3.2
Left Circumflex Artery
 Dmean (Gy) 1.61 ± 0.83 0.53–4.34 0.14 ± 0.08 0.04–0.25
 D2 (Gy) 1.87 (median) 0.75–48.66 0.27 ± 0.13 0.09–0.45
 Individual ratio D2/Dmean 1.3 (median) 0.8–43.4 2.2 ± 0.8 1.5–4.0
Left Main Coronary Artery
 Dmean (Gy) 1.28 ± 0.69 0.60–4.72 0.11 ± 0.05 0.04–0.21
 D2 (Gy) 1.39 (median) 0.69–49.45 0.25 ± 0.13 0.06–0.46
 Individual ratio D2/Dmean 1.2 (median) 1.0–35.6 1.2 ± 0.2 0.8–1.6
Right Coronary Artery
 Dmean (Gy) 0.74 ± 0.53 0.14–4.39 1.25 ± 0.41 0.68–2.01
 D2 (Gy) 1.38 ± 1.04 0.35–8.61 1.77 ± 0.74 0.33–3.54
 Individual ratio D2/Dmean 1.9 ± 0.4 1.1–2.9 1.4 ± 0.4 0.3–2.2
  1. BC breast cancer, SD standard deviation, MHD Mean heart dose, D2 minimal dose received by the most irradiated 2% of the structure volume, Dmean mean dose to the structure