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Table 2 Dosimetric parameters for heart and cardiac substructures including coronary arteries

From: Is mean heart dose a relevant surrogate parameter of left ventricle and coronary arteries exposure during breast cancer radiotherapy: a dosimetric evaluation based on individually-determined radiation dose (BACCARAT study)

 

Left-sided BC patients

N = 89

Right-sided BC patients

N = 15

Mean ± SD

Range

Mean ± SD

Range

Heart

 MHD (Gy)

2.95 ± 1.49

0.87–6.72

0.46 ± 0.12

0.25–0.67

 D2 (Gy)

26.80 ± 17.40

3.95–48.87

2.16 ± 0.90

1.11–3.57

 Individual ratio D2/MHD

8.4 ± 3.6

2.9–15.4

4.6 ± 0.6

3.6–5.8

Left Ventricle

 Dmean (Gy)

6.25 ± 3.53

1.16–13.42

0.09 ± 0.04

0.04–0.17

 D2 (Gy)

34.01 ± 16.93

4.49–55.48

0.34 ± 0.13

0.17–0.54

 Individual ratio D2/Dmean

5.7 ± 2.0

2.6–11.0

3.9 ± 0.7

2.6–5.3

Left Anterior Descending Artery

 Dmean (Gy)

15.68 ± 8.13

1.68–37.61

0.37 ± 0.15

0.13–0.54

 D2 (Gy)

37.97 ± 15.93

2.19–56.42

0.45 ± 0.17

0.19–0.61

 Individual ratio D2/Dmean

2.6 ± 0.9

1.3–6.0

2.3 ± 0.6

1.3–3.2

Left Circumflex Artery

 Dmean (Gy)

1.61 ± 0.83

0.53–4.34

0.14 ± 0.08

0.04–0.25

 D2 (Gy)

1.87 (median)

0.75–48.66

0.27 ± 0.13

0.09–0.45

 Individual ratio D2/Dmean

1.3 (median)

0.8–43.4

2.2 ± 0.8

1.5–4.0

Left Main Coronary Artery

 Dmean (Gy)

1.28 ± 0.69

0.60–4.72

0.11 ± 0.05

0.04–0.21

 D2 (Gy)

1.39 (median)

0.69–49.45

0.25 ± 0.13

0.06–0.46

 Individual ratio D2/Dmean

1.2 (median)

1.0–35.6

1.2 ± 0.2

0.8–1.6

Right Coronary Artery

 Dmean (Gy)

0.74 ± 0.53

0.14–4.39

1.25 ± 0.41

0.68–2.01

 D2 (Gy)

1.38 ± 1.04

0.35–8.61

1.77 ± 0.74

0.33–3.54

 Individual ratio D2/Dmean

1.9 ± 0.4

1.1–2.9

1.4 ± 0.4

0.3–2.2

  1. BC breast cancer, SD standard deviation, MHD Mean heart dose, D2 minimal dose received by the most irradiated 2% of the structure volume, Dmean mean dose to the structure