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Table 5 Comparison of predicted clinically relevant dose–volume indices derived from each TPS (XiO or RayStaion)

From: Comparison of gamma index based on dosimetric error and clinically relevant dose–volume index based on three-dimensional dose prediction in breast intensity-modulated radiation therapy

Predicted clinically relevant dose–volume indices

XiO Mean ± SD

RayStation Mean ± SD

P value

PTV D95% (Gy)

47.0 ± 0.5

46.8 ± 0.4

p < 0.001

Heart Dmean (Gy)

2.5 ± 0.9

2.4 ± 0.9

p < 0.001

Lung V5Gy (%)

23.7 ± 6.4

19.2 ± 5.8

p < 0.001

Lung V20Gy (%)

10.3 ± 4.8

10.0 ± 4.6

p < 0.005

TCP of PTV

0.9199 ± 0.0034

0.9184 ± 0.0029

p < 0.005

NTCP of Ipsilateral Lung

0.0079 ± 0.0074

0.0062 ± 0.0061

p < 0.001

NTCP of Heart

0.0034 ± 0.0037

0.0035 ± 0.0037

Not significant

  1. PTV D95%: dose coverage 95% volume of PTV. Heart Dmean: dose coverage mean volume of Heart. Lung V5Gy or V20Gy: volume receiving at least 5 Gy or 20 Gy of ipsilateral lung