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Table 2 Dose-volume parameters according to treatment (N = 30)

From: Preliminary result of definitive radiotherapy in patients with non-small cell lung cancer who have underlying idiopathic pulmonary fibrosis: comparison between X-ray and proton therapy

Characteristics

X-ray (n = 22)

Proton (n = 8)

p value

Clinical target volume (cm3)

73.3 ± 52.6

206.1 ± 100.6

0.007

Total lung

 Mean dose (cGy or CcGE)

809.8 ± 368.1

796.9 ± 475.2

0.938

 V5 (%)

28.4 ± 9.7

23.1 ± 11.6

0.216

 V10 (%)

19.8 ± 8.8

18.7 ± 10.5

0.782

 V20 (%)

13.1 ± 8.1

14.3 ± 8.6

0.717

Heart

 V45 (%)

0.2 ± 0.5

0.1 ± 0.2

0.855

Esophagus

 Maximum dose (cGy or CcGE)

1588.5 ± 1030.2

1261.4 ± 1216.3

0.469

 Mean dose (cGy or CcGE)

408.0 ± 301.4

257.9 ± 304.6

0.239

Spinal cord

 Maximum dose (cGy or CcGE)

1141.4 ± 761.5

1487.0 ± 1491.0

0.548

  1. VD percentage volume of organ receiving ≥ D Gy
  2. Data are presented as mean ± SD