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Table 1 Clinical characteristics according to treatment (N = 30)

From: Preliminary result of definitive radiotherapy in patients with non-small cell lung cancer who have underlying idiopathic pulmonary fibrosis: comparison between X-ray and proton therapy

Characteristics X-ray (n = 22) Proton (n = 8) p value
Age [years; median (range)] 75 (55–84) 77 (62–85) 0.640
Sex
 Female 0 (0%) 1 (12.5%) 0.092
 Male 22 (100%) 7 (87.5%)  
Smoking Status
 Never smoker 0 (0%) 1 (12.5%) 0.092
 Current or Ex-smoker 22 (100%) 7 (87.5%)  
ECOG performance
 0–1 13 (59.1%) 8 (100%) 0.031
 2–3 9 (40.9%) 0 (0%)  
Clinical Stage
 IA-IB 15 (68.2%) 4 (50.0%) 0.361
 IIA-IIB 7 (31.8%) 4 (50.0%)  
Histology
 Adenocarcinoma 5 (31.3%) 2 (28.6%) 0.775
 Squamous cell carcinoma 10 (62.5%) 5 (71.4%)  
 Others 1 (6.2%) 0 (0%)  
 Not proven 6 1  
Pulmonary function test
FEV1
 > 50% 21 (95.5%) 8 (100%) 0.540
 ≤ 50% 1 (4.5%) 0 (0%)  
DLCO
 > 60% 9 (40.9%) 2 (25.0%) 0.424
  ≤ 60% 13 (59.1%) 6 (75.0%)  
DLCO
 > 40% 20 (90.9%) 7 (87.5%) 0.783
 ≤ 40% 2 (9.1%) 1 (12.5%)  
GAP index
 1 9 (40.9%) 1 (12.5%) 0.144
 2–3 13 (59.1%) 7 (87.5%)  
  1. ECOG Eastern Cooperative Oncology Group, FEV1 forced expiratory volume in 1 s; DLCO, diffusing capacity of the lung for carbon monoxide