Tumor location as an indication for adjuvant radiotherapy in pT3N0 rectal cancer after surgery

Radiation Oncology

Table 8 Multivariate Analyses of DFS, LRFS, and DMFS for subgroup patients with lower rectal cancer(tumor location< 7 cm from AV)

Variable	DFS		LRFS		DMFS
Variable	HR(95%CI)	P value	HR(95%CI)	P value	HR(95%CI)	P value
Tumor volume, cm³ < 18 vs ≥18	0.429 (0.183–0.906)	0.047	NA		0.217 (0.061–0.769)	0.018
Adjuvant radiotherapy yes vs no	0.358 (0.150–0.851)	0.020	0.314 (0.102–0.964)	0.043	0.345 (0.124–0.959)	0.041

Abbreviations: DFS disease-free survival, LRFS local recurrence-free survival, DMFS distant metastasis-free survival, NA not available, CI confidence interval, HR hazard ratio, AV anal verge

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