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Table 4 Univariate analysis of dosimetric factors related to the occurrence of grade ≥ 2 acute radiation pneumonitis

From: Excluding PTV from lung volume may better predict radiation pneumonitis for intensity modulated radiation therapy in lung cancer patients

Factors

Odds Ratio

95% CI

P Value*

V5 Lung-PTV

1.054

1.014–1.096

0.008

V5 Lung-PGTV

1.048

1.007–1.091

0.023

V5 Total Lung

1.049

1.007–1.094

0.022

V20 Lung-PTV

1.204

1.059–1.369

0.005

V20 Lung-PGTV

1.164

1.039–1.305

0.009

V20 Total Lung

1.137

1.015–1.272

0.026

MLD Lung-PTV

1.421

1.116–1.809

0.004

MLD Lung-PGTV

1.271

1.038–1.557

0.021

MLD Total Lung

1.232

1.012–1.501

0.038

  1. Abbreviation: CI confidence interval, PTV planning target volume, PGTV planning gross tumor volume, V5/20 volume of lung receiving a dose ≥5/20 Gy, MLD mean lung dose
  2. *By univariate logistic regression analysis