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Table 4 Univariate analysis of dosimetric factors related to the occurrence of grade ≥ 2 acute radiation pneumonitis

From: Excluding PTV from lung volume may better predict radiation pneumonitis for intensity modulated radiation therapy in lung cancer patients

Factors Odds Ratio 95% CI P Value*
V5 Lung-PTV 1.054 1.014–1.096 0.008
V5 Lung-PGTV 1.048 1.007–1.091 0.023
V5 Total Lung 1.049 1.007–1.094 0.022
V20 Lung-PTV 1.204 1.059–1.369 0.005
V20 Lung-PGTV 1.164 1.039–1.305 0.009
V20 Total Lung 1.137 1.015–1.272 0.026
MLD Lung-PTV 1.421 1.116–1.809 0.004
MLD Lung-PGTV 1.271 1.038–1.557 0.021
MLD Total Lung 1.232 1.012–1.501 0.038
  1. Abbreviation: CI confidence interval, PTV planning target volume, PGTV planning gross tumor volume, V5/20 volume of lung receiving a dose ≥5/20 Gy, MLD mean lung dose
  2. *By univariate logistic regression analysis