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Table 3 Difference of dosimetric factors between RP2 and non-RP2 groups

From: Excluding PTV from lung volume may better predict radiation pneumonitis for intensity modulated radiation therapy in lung cancer patients

Factors Non-RP2 RP2 P Value*
Median Range Median Range
Lung-PTV method
 V5 Lung-PTV (%) 48 23–76 50.5 31–78 0.046
 V20 Lung-PTV (%) 18 8–26 19 15–31 0.035
 MLD Lung-PTV (Gy) 10.3 6.0–15.1 11.3 7.9–15.6 0.016
Lung-PGTV method
 V5 Lung-PGTV (%) 51 26–76 52.5 33–80 0.085
 V20 Lung-PGTV (%) 22 11–31 24 18–34 0.046
 MLD Lung-PGTV (Gy) 12.1 7.0–17.0 13.1 9.7–18.1 0.076
Total Lung Method
 V5 Total Lung (%) 52 27–77 53 36–80 0.091
 V20 Total Lung (%) 23 11–31 24 20–36 0.080
 MLD Total Lung (Gy) 12.6 7.2–17.3 13.7 10.1–19.6 0.097
  1. Abbreviation: RP2 radiation pneumonitis≥ grade 2, PTV planning target volume, PGTV planning gross tumor volume, V5/20 volume of lung receiving a dose ≥5/20 Gy, MLD mean lung dose
  2. *By Mann-Whitney U test