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Table 2 Difference of dosimetric factors among three lung definition methods

From: Excluding PTV from lung volume may better predict radiation pneumonitis for intensity modulated radiation therapy in lung cancer patients

Factors

Mean Difference

95% CI

P Value*

V5 (%)

Lung-PTV vs. Lung-PGTV

2.2

2.0–2.4

< 0.001

Lung-PTV vs. Total Lung

2.7

2.5–3.0

< 0.001

Lung-PGTV vs. Total Lung

0.6

0.4–0.7

< 0.001

V20 (%)

Lung-PTV vs. Lung-PGTV

3.5

3.3–3.8

< 0.001

Lung-PTV vs. Total Lung

4.5

4.2–4.8

< 0.001

Lung-PGTV vs. Total Lung

1.0

0.8–1.1

< 0.001

MLD (Gy)

Lung-PTV vs. Lung-PGTV

1.7

1.6–1.8

< 0.001

Lung-PTV vs. Total Lung

2.3

2.1–2.4

< 0.001

Lung-PGTV vs. Total Lung

0.6

0.5–0.7

< 0.001

  1. Abbreviation: PTV planning target volume, PGTV planning gross tumor volume, V5/20 volume of lung receiving a dose ≥5/20 Gy, MLD mean lung dose
  2. *By repeated analysis of variance test (ANOVA)
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Radiation Oncology

ISSN: 1748-717X

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