Clinical outcomes of radiation therapy for clinical T4b oesophageal cancer with airway invasion

Radiation Oncology

Table 2 Clinical courses of patients with malignant esophageal fistula at initial diagnosis

No.	Age/Sex	PS	Site	Treatment	RT technique	Change of fistula	Diet at last f/u	Survival (month)	Status
1	53/M	2	BEF	Palliative RT, 30Gy/10Fx	3DCRT	Closed at 2 months after RT	Tube feeding	2	Dead of unknown cause
2	56/F	1	TEF	Definitive CCRT with FP, 66Gy/33Fx	3DCRT	Closed^a	Oral intake	93	Alive with no evidence of disease^a
3	68/M	1	TEF	Definitive RT alone, 60Gy/20Fx	3DCRT	Closed at 2 months after RT	Oral intake	6	Dead of disease
4	62/M	1	TEF	Definitive CCRT with FP, 70Gy/35Fx	3DCRT	No change	Tube feeding	8	Dead of unknown cause
5	58/M	2	TEF	Palliative RT, 45Gy/18Fx	3DCRT	Aggravated	Tube feeding	10	Dead of disease (aspiration pneumonia)
6	60/M	1	BEF	Definitive RT alone, 22Gy/11Fx (incomplete)	3DCRT	No change	Tube feeding	3	Dead of disease
7	54/M	1	T-BEF	Definitive CCRT with FP, 60Gy/30Fx	IMRT	No change	Tube feeding	12	Alive with disease

Abbreviation: PS performance status, RT radiotherapy, BEF bronchoesophageal fistula, TEF tracheoesophageal fistula, T-BEF tracheobronchial esophageal fistula, CCRT Concurrent chemoradiotherapy, 3DCRT 3-dimensional conformal radiation therapy, IMRT Intensity-modulated radiotherapy
^aClosing of fistula was found at 6 months’ follow-up. She performed Ivor-Lewis operation due to persistent residual mass and pathology showed complete response

ISSN: 1748-717X