Table 3 Univariate analysis demonstrating factors associated with OS
Factor | OS P-value | HR (95% CI) |
|---|---|---|
Treatment modality (CCRT vs chemotherapy) | 0.011 | 0.626 (0.437–0.898) |
Sex (male vs female) | 0.677 | 0.918 (0.615–1.371) |
Age (≤60 years vs > 60 years) | 0.836 | 1.037 (0.734–1.465) |
KPS score (≤80 vs > 80) | 0.920 | 1.021 (0.679–1.536) |
Primary tumor location | ||
cervical | reference | |
upper thoracic | 0.757 | 0.861 (0.333–2.225) |
middle thoracic | 0.800 | 1.125 (0.450–2.812) |
lower thoracic | 0.859 | 1.089 (0.427–2.774) |
T- Stage (T1 + 2 vs T3 + 4) | 0.096 | 0.667 (0.413–1.075) |
N- Stage (N0 vs N+) | 0.867 | 0.956 (0.566–1.615) |
Dysphagia score | ||
0 (asymptomatic) | reference | |
1 (eat solid diet with some dysphagia) | 0.564 | 0.743 (0.272–2.034) |
2 (eat semisolid diet) | 0.615 | 1.239 (0.537–2.858) |
3 (drink liquid diet) | 0.880 | 1.063 (0.481–2.346) |
4 (complete dysphagia) | 0.870 | 1.072 (0.466–2.467) |
Number of metastases organs (solitary vs multiple metastasis) | 0.013 | 0.621 (0.426–0.905) |
Chemotherapy regimens (PTX + DDP vs 5-Fu + DDP) | 0.109 | 0.747 (0.523–1.067) |
Chemotherapy cycles (≤2 vs > 2) | 0.910 | 1.021 (0.711–1.466) |