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Table 2 The comparison of dose values (in Gy) at organs at risk points (fovea, optic disc center, lens center and lacrimal glad center) for four different plaque positions (#1-#4) [15] of the 16 mm COMS plaque loaded with 125I seeds (model 6711) calculated in our in-house program with average off-axis dose values calculated from treatment planning systems used in Rivard et al.’s study

From: A practical approach to estimating optic disc dose and macula dose without treatment planning in ocular brachytherapy using 125I COMS plaques

Plaque position Off-axis location Current Study Data from Table III in Rivard et al. [15] \( \left|{\mathrm{D}}_{\mathrm{diff}}^{\mathrm{Rel}}\left(\%\right)\right| \)
#1 Fovea 16.50 16.3 1.25
Optic disc 11.29 11.2 0.79
Lens 21.59 21.5 0.40
Lacrimal gland 40.92 39.2 4.39
#2 Fovea 16.50 16.3 1.25
Optic disc 28.02 27.6 1.52
Lens 21.59 21.5 0.40
Lacrimal gland 7.19 7.1 1.22
#3 Fovea 16.50 16.3 1.25
Optic disc 16.48 16.3 1.08
Lens 21.59 21.5 0.40
Lacrimal gland 40.92 39.2 4.40
#4 Fovea 16.50 16.3 1.25
Optic disc 16.48 16.3 1.08
Lens 21.59 21.5 0.40
Lacrimal gland 7.19 7.1 1.22
  1. Dose values were calculated for a prescribed dose of approximately 85 Gy to a central-axis depth of 5 mm (Sk = 4.752 U and irradiation time = 100 h) using a line source approximation of the AAPM TG-43 formalism and homogeneous water phantoms. \( \left|{\mathrm{D}}_{\mathrm{diff}}^{\mathrm{Rel}}\left(\%\right)\right| \) is a modulus of a relative percent difference in dose between the two studies