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Table 2 Dose constraints for the organs at risk adhering to the local guidelines and QUANTEC [26]

From: Comparison of different treatment planning approaches for intensity-modulated proton therapy with simultaneous integrated boost for pancreatic cancer

OAR Dose constraint
Spinal cord Dmax ≤ 45 Gy
Liver Dmean ≤ 30 Gy
V30Gy ≤ 30%
Kidney Dmean ≤ 18 Gy
V12Gy ≤ 55%
V20Gy ≤ 32%
Stomach Dmax ≤ 54 Gy
V50Gy ≤ 2%
V45Gy ≤ 25%
Duodenum Dmax ≤ 55 Gy
V45Gy ≤ 25%
Large Bowel V15Gy ≤ 120 ccm
Small Bowel V15Gy ≤ 120 ccm
  1. Abbreviations: Dmax maximum dose, Dmean mean dose, VxGy volume receiving x-Gy