Table 3 The subgroup analysis of the bone density (HU = Hounsfield units) in metastatic bone before RT (baseline), as well as 3 and 6 months after RT
IMRT group | 3DCRT group | Differences between groups | |||||||
|---|---|---|---|---|---|---|---|---|---|
n | Median | SD | n | Median | SD | HL | 95% CI | p-value | |
Mixed | |||||||||
HU Baseline | 17 | 242.0 | 100.1 | 10 | 230.5 | 77.3 | −41.5 | − 128.0-40.0 | 0.238 |
HU T2 | 11 | 360.0 | 153.1 | 5 | 418.0 | 89.4 | 58.0 | − 114-204.0 | 0.450 |
HU T3 | 9 | 355.0 | 174.1 | 4 | 559.5 | 132.0 | 190.5 | −61.0-416.0 | 0.190 |
3 months | |||||||||
HU T0-T2 | 11 | 102.0 | 92.2 | 5 | 164.0 | 68.4 | 59.0 | −43.0-174.0 | 0.213 |
HU T0-T2 (%) | 11 | 38.8 | 41.2 | 5 | 60.8 | 48.5 | 25.7 | −32.5-89.5 | 0.256 |
6 months | |||||||||
HU T0-T3 | 9 | 176.0 | 123.1 | 4 | 301.0 | 89.4 | 161.5 | 73.0–341.0 | 0.025 |
HU T0-T3 (%) | 9 | 55.0 | 61.1 | 4 | 145.9 | 42.2 | 80.7 | 8.7–155.1 | 0.037 |
Osteolytic | |||||||||
HU Baseline | 6 | 178.5 | 74.3 | 14 | 156.5 | 60.9 | 20.0 | −60.0 − 82.0 | 0.536 |
HU T2 | 4 | 269.5 | 198.4 | 8 | 181.5 | 70.8 | 84.0 | -82.0-387.0 | 0.270 |
HU T3 | 4 | 153.0 | 127.7 | 3 | 295.0 | 82.8 | 126.5 | − 184.0-277.0 | 0.377 |
3 months | |||||||||
HU T0-T2 | 4 | 35.5 | 171.2 | 8 | 16.0 | 38.0 | 19.5 | −53.0-364.0 | 0.489 |
HU T0-T2 (%) | 4 | 20.3 | 83.11 | 8 | 9.3 | 21.2 | 12.2 | −27.5-178.4 | 0.489 |
6 months | |||||||||
HU T0-T3 | 4 | 10.0 | 95.3 | 3 | 64.0 | 89.1 | 110.0 | −60.0-315.0 | 0.212 |
HU T0-T3 (%) | 4 | −0.8 | 55.4 | 3 | 27.7 | 55.0 | 46.9 | −61.2-174.2 | 0.377 |
Osteoblastic | |||||||||
HU Baseline | 7 | 419.0 | 247.6 | 6 | 426.0 | 159.8 | −94.5 | − 415.0-172.0 | 0.520 |
HU T2 | 5 | 574.0 | 327.0 | 6 | 481.5 | 174.4 | 145.5 | − 284.0-604.0 | 0.411 |
HU T3 | 5 | 700.0 | 374.8 | 5 | 475.0 | 196.4 | 255.0 | − 367.0-711.0 | 0.296 |
3 months | |||||||||
HU T0-T2 | 5 | 52.0 | 188.3 | 6 | 13.0 | 103.3 | 45.0 | − 311.0-155.0 | 0.647 |
HU T0-T2 (%) | 5 | 15.4 | 35.8 | 6 | 3.1 | 27.5 | 3.0 | −57.0-30.8 | 1.000 |
6 months | |||||||||
HU T0-T3 | 5 | 130.0 | 241.7 | 5 | 57.0 | 102.9 | 42.0 | − 408.0-224.0 | 0.676 |
HU T0-T3 (%) | 5 | 15.4 | 47.2 | 5 | 13.6 | 27.3 | 1.7 | −77.9-53.4 | 1.000 |