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Table 4 Univariate analysis to assess the impact of dose factors on the appearance of CTCAE grad II-III toxicity and moist desquamation in 276 patients

From: Acute radiodermatitis in modern adjuvant 3D conformal radiotherapy for breast cancer - the impact of dose distribution and patient related factors

Variables CTCAE Moist Desquamation
II°/III° P value No Yes P value
Dmax CTV (Gy) 52.9 (50.0–59.8) 52.9 (47.7–61.8) 0.91 52.9 (50.0–61.84) 53.1 (47.7–55.5) 0.34
Dmax skin (Gy) 53.3 (50.2–60.1) 53.4 (48.4–62.1) 0.64 52.4 (47.9–61.0) 52.6 (47.6–54.2) 0.93
Dmean skin (Gy) 36.5 (23.0–38.7) 36.6 (19.8–38.9) 0.66 36.6 (19.8–38.7) 36.4 (20.5–38.9) 0.10
V107% CTV (cm3) 0.4 (0.0–79.0) 0.8 (0–45.8) 0.54 0,6 (0–79.0) 1.3 (0–45.8) 0.04*
V105% Skin (cm3) 0.3 (0.0–8.7) 0.6 (0.0–46.5) 0.27 0.4 (0.0–17.2) 0.9 (0.0–46.5) 0.03*
V80% Skin (cm3) 124.7 (35.3–293.9) 134.3 (5.9–282.6) 0.06 126.9 (5.9–293.9) 147.7 (67.9–282.6) < 0.01*
  1. Mean values ± SD. *p < 0.05