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Table 2 Univariable and multivariable Cox regression analysis of overall survival

From: Relation of baseline neutrophil-to-lymphocyte ratio to survival and toxicity in head and neck cancer patients treated with (chemo-) radiation

  univariable analysis multivariable analysis
HR (95% CI) P HR (95% CI) P
Age per 10 years older 1.32 (1.03–1.69) 0.026*   
Gender male (vs. female) 1.17 (0.61–2.25) 0.639   
Smoking status never smoker (vs. current/past) 0.66 (0.20–2.19) 0.492   
Karnofsky Performance Status per 10 higher 0.76 (0.62–0.92) 0.005* 0.76 (0.62–0.98) 0.030*
UICC stage IVA-B (vs. I-III) 1.87 (1.01–3.47) 0.045*   
Tumor grade G3 (vs. G1-G2) 0.91 (0.54–1.54) 0.731   
Hemoglobin per 1 g/dL higher 0.89 (0.77–1.04) 0.143   
log NLR per 1 log NLR higher 1.81 (1.16–2.81) 0.009* 1.58 (1.01–2.47) 0.043*
log PLR per 1 log PLR higher 1.62 (0.99–2.63) 0.054   
  1. CI confidence interval, G tumor grade, HR hazard ratio, log NLR natural logarithm of neutrophil-to-lymphocyte ratio, log PLR natural logarithm of platelet-to-lymphocyte ratio, UICC Union for International Cancer Control; *statistically significant