Estimation of the risk for radiation-induced liver disease following photon- or proton-beam radiosurgery of liver metastases

Table 3 Mean doses (2 Gy per-fraction), NTCPs and ΔNTCP for the healthy part of the liver

Patient #	Liver mean dose (Gy (IsoE))		NTCP for RILD (%)		ΔNTCP (%)
Patient #	SBRT	IMPT^a	SBRT	IMPT^a	ΔNTCP (%)
1	38	18 (15–21)	38	0 (0–0)	- 38
2	49	26 (21–30)	98	1 (0–5)	−97
3	60	39 (31–45)	100	53 (5–91)	−47
4	51	33 (30–35)	99	10 (4–16)	- 89
5	30	31 (29–33)	3	5 (1–5)	2
6	39	22 (17–25)	44	0 (0–0)	- 44
7	26	19 (17–20)	0	0 (0–0)	0
8	18	14 (9–18)	0	0 (0–0)	0
9	34	15 (14–16)	17	0 (0–0)	- 17
10	56	40 (36–41)	100	59 (27–73)	- 41

^aThe values in parentheses represent the range of values of the mean doses and NTCPs obtained for the simulated uncertainty scenarios in the IMPT plans

ISSN: 1748-717X