Skip to main content

Table 2 Radiation doses according to TAPSE decline

From: Decreases in TGF-β1 and PDGF levels are associated with echocardiographic changes during adjuvant radiotherapy for breast cancer

 

≥15% decrease in TAPSE (n = 20)

< 15% decrease in TAPSE (n = 46)

 

Md (IQR)

Md (IQR)

p

Heart

 Dmean (Gy)

3.39 (0.8–4.2)

1.8 (0.8–3.5)

0.343

 Dmax (Gy)

46.1 (5.3–49.0)

45.9 (11.8–47.5)

0.676

 V45 (%)

0.2 (0–1.3)

0.1 (0–0.7)

0.630

 V20 (%)

4.3 (0–5.2)

1.4 (0–4.8)

0.330

LAD

 Dmean (Gy)

23.7 (0.3–28.5)

10.3 (2.3–23.5)

0.414

 Dmax (Gy)

44.1(0.7–48.1)

40.8 (5.0–46.1)

0.460

 V45 (%)

0(0–5.2)

0(0–7.3)

0.663

 V20 (%)

43.6 (0–67.6)

19.7(0–54.9)

0.193

Left ventricle

 Dmean (Gy)

4.6 (0.2–7.2)

2.7 (1.2–5.5)

0.273

 Dmax (Gy)

44.6 (0.8–47.6)

44.1 (5.0–46.7)

0.691

 V45 (%)

0.1 (0–2.0)

0 (0–0.4)

0.360

 V20 (%)

6.0 (0–11.7)

1.7 (0–7.8)

0.192

 V10 (%)

8.8 (0–15.1)

3.4 (0–11.0)

0.150

Right ventricle

 Dmean (Gy)

2.0 (0.8–7.2)

1.6 (0.9–2.9)

0.692

 Dmax (Gy)

27.6 (3.1–43.4)

21.3 (3.3–42.8)

0.988

 V45 (%)

0 (0–0)

0 (0–0)

0.925

 V20 (%)

0.1 (0–1.3)

0 (0–1.3)

0.848

 V10 (%)

0.7 (0–3.6)

0.1 (0–3.8)

0.714

Ipsilateral lung

 Dmean (Gy)

8.1 (6.4–9.1)

7.7 (6.2–9.0)

0.484

 Dmax (Gy)

49.2 (46.2–52.7)

48.5 (47.1–51.6)

0.994

  1. Md median, IQR interquartile range, Dmean mean radiation dose to the structure, Dmax maximum radiation dose within the structure, V45 percentage of the structure volume receiving 45 Gy of radiation, V20 percentage of the structure volume receiving 20 Gy of radiation, V10 percentage of the structure volume receiving 10 Gy of radiation, LAD left anterior descending coronary artery