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Table 2 Radiation doses according to TAPSE decline

From: Decreases in TGF-β1 and PDGF levels are associated with echocardiographic changes during adjuvant radiotherapy for breast cancer

  ≥15% decrease in TAPSE (n = 20) < 15% decrease in TAPSE (n = 46)  
Md (IQR) Md (IQR) p
Heart
 Dmean (Gy) 3.39 (0.8–4.2) 1.8 (0.8–3.5) 0.343
 Dmax (Gy) 46.1 (5.3–49.0) 45.9 (11.8–47.5) 0.676
 V45 (%) 0.2 (0–1.3) 0.1 (0–0.7) 0.630
 V20 (%) 4.3 (0–5.2) 1.4 (0–4.8) 0.330
LAD
 Dmean (Gy) 23.7 (0.3–28.5) 10.3 (2.3–23.5) 0.414
 Dmax (Gy) 44.1(0.7–48.1) 40.8 (5.0–46.1) 0.460
 V45 (%) 0(0–5.2) 0(0–7.3) 0.663
 V20 (%) 43.6 (0–67.6) 19.7(0–54.9) 0.193
Left ventricle
 Dmean (Gy) 4.6 (0.2–7.2) 2.7 (1.2–5.5) 0.273
 Dmax (Gy) 44.6 (0.8–47.6) 44.1 (5.0–46.7) 0.691
 V45 (%) 0.1 (0–2.0) 0 (0–0.4) 0.360
 V20 (%) 6.0 (0–11.7) 1.7 (0–7.8) 0.192
 V10 (%) 8.8 (0–15.1) 3.4 (0–11.0) 0.150
Right ventricle
 Dmean (Gy) 2.0 (0.8–7.2) 1.6 (0.9–2.9) 0.692
 Dmax (Gy) 27.6 (3.1–43.4) 21.3 (3.3–42.8) 0.988
 V45 (%) 0 (0–0) 0 (0–0) 0.925
 V20 (%) 0.1 (0–1.3) 0 (0–1.3) 0.848
 V10 (%) 0.7 (0–3.6) 0.1 (0–3.8) 0.714
Ipsilateral lung
 Dmean (Gy) 8.1 (6.4–9.1) 7.7 (6.2–9.0) 0.484
 Dmax (Gy) 49.2 (46.2–52.7) 48.5 (47.1–51.6) 0.994
  1. Md median, IQR interquartile range, Dmean mean radiation dose to the structure, Dmax maximum radiation dose within the structure, V45 percentage of the structure volume receiving 45 Gy of radiation, V20 percentage of the structure volume receiving 20 Gy of radiation, V10 percentage of the structure volume receiving 10 Gy of radiation, LAD left anterior descending coronary artery