Table 4 Comparison of dose to organs at risk for 4 planning treatment: PTV66, PTV FDG 70%, PTV F-miso, PTV FDG 42 Gy
From: FDG and FMISO PET-guided dose escalation with intensity-modulated radiotherapy in lung cancer
Scenario | Boost target volume | Dose-volume constraint to organ at risk | |||
|---|---|---|---|---|---|
Mean lung dose (Gy) | D2% spinal cord (Gy) | V35 heart (%) | V50 oesophagus (%) | ||
Reference plan | 11.5 (±0.5) | 32.7 (±2.1) | 5** (±1.7) | 20.5 (±2.7) | |
Scenario 2 | FDG Hotspot | 11.7 (±0.5) | 32 (±2.1) | 5.3 (±1.8) | 20.4 (±2.6) |
Scenario 3 | Fmiso | 11.8 (±0.5) | 31.6 (±2.1) | 5.2 (±1.9) | 21 (±2.6) |
Scenario 4 | FDG per treatment | 13.4 (±1.5) | 32.2 (±2.3) | 5.4** (±1.8) | 20.8 (±2.7) |
p value | 0.2 | 0.7 | 0.03 | 0.4 | |