Table 3 Comparison of dose to CTV or BTV for 4 planning treatment: CTV66, BTV FDG 70%, BTV F-miso, BTV FDG 42 Gy
From: FDG and FMISO PET-guided dose escalation with intensity-modulated radiotherapy in lung cancer
Scenario | Boost target volume | Mean (± SE) doses to target volumes (Gy) | ||||
|---|---|---|---|---|---|---|
CTV66 | BTV FDG 70% | BTV FMISO | BTV FDG 42Gy | p value | ||
Reference plan (66 Gy) | 65.1 (± 0.35) | 67.1 (± 0.32) | 66.9 (± 0.38) | 66.8 (± 0.39) | NA | |
Scenario 2 | 18FDG Hotspot | 65.9 (± 0.47) | 74.3 (± 0.32) | 70.4 (± 0.86) | 70.4 (± 0.88) | 0.001 |
Scenario 3 | 18F-miso | 65.9 (± 0.53) | 72.6 (± 0.86) | 74.6 (± 0.33) | 71.7 (± 0.9) | 0.001 |
Scenario 4 | 18FDG per RT | 66.8 (± 0.42) | 73.5 (± 0.68) | 72.5 (± 0.7) | 74.6 (± 0.31) | 0.001 |