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Table 2 Dosimetric comparison between coverage and OAR doses with DIBH versus FB

From: Reduction in low-dose to normal tissue with the addition of deep inspiration breath hold (DIBH) to volumetric modulated arc therapy (VMAT) in breast cancer patients with implant reconstruction receiving regional nodal irradiation

Structure

Parameter

FB

DIBH

p value

PTV

D95 (%)

95

95

V95 (%)

95

95

D05 (%)

111.9 ± 2.2

110.4 ± 0.8

0.07

IMN

D95 (%)

99.3 ± 4.2

100.9 ± 0.8

0.48

Ipsilateral Lung

V20 Gy (%)

28.2 ± 4.7

26.4 ± 3.9

0.1

V10 Gy (%)

47.1 ± 6.9

44.7 ± 6.4

0.03

V05 Gy (%)

77.2 ± 8

71.4 ± 7.5

0.01

Mean (Gy)

15.7 ± 1.8

14.9 ± 1.6

0.03

Contralateral Lung

V20 Gy (%)

0.9 ± 1.5

0.7 ± 0.9

0.63

V05 Gy (%)

48.5 ± 12.9

33.1 ± 18.3

< 0.01

Total Lung

V20 Gy (%)

13.1 ± 2.6

12.4 ± 2.1

0.12

V10 Gy (%)

28.6 ± 6.1

24.6 ± 5.4

0.01

V05 Gy (%)

61.3 ± 9.7

50.5 ± 12.2

< 0.01

Mean (Gy)

10.3 ± 1.3

9.2 ± 1.4

< 0.01

Heart

V25 Gy (%)

3.1 ± 2.1

1 ± 1.5

< 0.01

V15 Gy (%)

10 ± 4.4

2.9 ± 2.9

< 0.01

V05 Gy (%)

64.9 ± 14.2

35.3 ± 9.9

< 0.01

Mean (Gy)

8.2 ± 1.4

5.3 ± 1

< 0.01

Dmax (Gy)

47.7 ± 7.5

38.3 ± 11.2

< 0.01

LAD

Dmax (Gy)

40.7 ± 12.1

30.8 ± 12.6

0.02

Contralateral Breast/Implant

V04 Gy (%)

48.5 ± 15.2

35.3 ± 12.9

< 0.01

V03 Gy (%)

67.3 ± 16.8

49 ± 14.8

< 0.01

Mean (Gy)

5.7 ± 1.4

5.1 ± 1.4

0.16

Esophagus

Dmax (Gy)

35.1 ± 8

33.1 ± 11

0.56

Thyroid

Mean (Gy)

13.4 ± 1.4

13.9 ± 2.1

0.87

Brachial Plexus

Dmax (Gy)

51 ± 1.1

51.5 ± 1.3

0.29