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Table 2 Dosimetric comparison between coverage and OAR doses with DIBH versus FB

From: Reduction in low-dose to normal tissue with the addition of deep inspiration breath hold (DIBH) to volumetric modulated arc therapy (VMAT) in breast cancer patients with implant reconstruction receiving regional nodal irradiation

Structure Parameter FB DIBH p value
PTV D95 (%) 95 95
V95 (%) 95 95
D05 (%) 111.9 ± 2.2 110.4 ± 0.8 0.07
IMN D95 (%) 99.3 ± 4.2 100.9 ± 0.8 0.48
Ipsilateral Lung V20 Gy (%) 28.2 ± 4.7 26.4 ± 3.9 0.1
V10 Gy (%) 47.1 ± 6.9 44.7 ± 6.4 0.03
V05 Gy (%) 77.2 ± 8 71.4 ± 7.5 0.01
Mean (Gy) 15.7 ± 1.8 14.9 ± 1.6 0.03
Contralateral Lung V20 Gy (%) 0.9 ± 1.5 0.7 ± 0.9 0.63
V05 Gy (%) 48.5 ± 12.9 33.1 ± 18.3 < 0.01
Total Lung V20 Gy (%) 13.1 ± 2.6 12.4 ± 2.1 0.12
V10 Gy (%) 28.6 ± 6.1 24.6 ± 5.4 0.01
V05 Gy (%) 61.3 ± 9.7 50.5 ± 12.2 < 0.01
Mean (Gy) 10.3 ± 1.3 9.2 ± 1.4 < 0.01
Heart V25 Gy (%) 3.1 ± 2.1 1 ± 1.5 < 0.01
V15 Gy (%) 10 ± 4.4 2.9 ± 2.9 < 0.01
V05 Gy (%) 64.9 ± 14.2 35.3 ± 9.9 < 0.01
Mean (Gy) 8.2 ± 1.4 5.3 ± 1 < 0.01
Dmax (Gy) 47.7 ± 7.5 38.3 ± 11.2 < 0.01
LAD Dmax (Gy) 40.7 ± 12.1 30.8 ± 12.6 0.02
Contralateral Breast/Implant V04 Gy (%) 48.5 ± 15.2 35.3 ± 12.9 < 0.01
V03 Gy (%) 67.3 ± 16.8 49 ± 14.8 < 0.01
Mean (Gy) 5.7 ± 1.4 5.1 ± 1.4 0.16
Esophagus Dmax (Gy) 35.1 ± 8 33.1 ± 11 0.56
Thyroid Mean (Gy) 13.4 ± 1.4 13.9 ± 2.1 0.87
Brachial Plexus Dmax (Gy) 51 ± 1.1 51.5 ± 1.3 0.29