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Table 4 Hazard ratios for distant metastasis free survival with 95% CI in 344 lymph node negative breast cancer patients with measures of effect modification

From: Molecular signature of response to preoperative radiotherapy in locally advanced breast cancer

MAP3K4 level

Radiotherapy

Hazard Ratio

(95% CI)

p-value

low

no

Reference = 1

  

low

yes

1.33

(0.38, 4.63)

0.652

high

no

1.97

(0.56, 6.97)

0.294

high

yes

3.21

(1.02, 10.15)

0.047*

  1. Measure of effect modification on additive scale: RERI (95% CI) 0.91 (−0.56, 2.39); P = 0.226
  2. Measure of effect modification on multiplicative scale: ratio of HRs (95% CI) 1.23 (0.31, 4.90); P = 0.773
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Radiation Oncology

ISSN: 1748-717X

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