Table 3 Clinical factors potentially influencing colostomy-free survival

Endpoint

Parameter

HR

95%CI

p

HR

95%CI

p

HR

95%CI

p

CSF

SIB

0.90

0.53,1.54

0.703

1.18

0.67,2.09

0.560

1.15

0.65,2.04

0.621

SIB on the first 24 months

0.72

0.38,1.34

0.297

0.95

0.49,1.84

0.877

0.95

0.48,1.85

0.871

Sex (M vs F)

1.64

0.93,2.90

0.087

1.60

0.90,2.84

0.109

Age

1.02

1.00,1.04

0.119

1.02

1.00,1.04

0.124

Stage III vs I-II

1.78

1.03,3.05

0.037

1.83

1.04,3.22

0.037

G3 vs G2-G1

0.82

0.40,1.71

0.603

0.85

0.41,1.77

0.668

OS

SIB

1.15

0.61,2.17

0.674

1.71

0.86,3.40

0.127

1.51

0.77,2.98

0.235

Sex (M vs F)

2.64

1.38,5.07

0.003

2.77

1.43,5.37

0.003

Age

1.03

1.00,1.06

0.043

1.03

1.00,1.06

0.031

Stage III vs I-II

2.27

1.17,4.38

0.015

2.64

1.30,5.34

0.007

G3 vs G2-G1

1.42

0.66,3.06

0.376

1.48

0.68,3.23

0.326

CIC

SIB

0.71

0.34,1.47

0.352

0.87

0.41,1.85

0.713

0.85

0.39,1.83

0.675

Sex (M vs F)

0.93

0.39,2.18

0.863

0.83

0.34,2.05

0.690

Age

1.00

0.98,1.03

0.765

1.00

0.98,1.02

0.878

Stage III vs I-II

2.09

0.99,4.38

0.052

2.13

0.97,4.70

0.061

G3 vs G2-G1

0.44

0.13,1.48

0.184

0.43

0.13,1.45

0.173