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Table 3 Clinical factors potentially influencing colostomy-free survival

From: Comparing simultaneous integrated boost vs sequential boost in anal cancer patients: results of a retrospective observational study

  Univariable Multivariable SIB vs SeqB,
Propensity score adjusted
Endpoint Parameter HR 95%CI p HR 95%CI p HR 95%CI p
CSF SIB 0.90 0.53,1.54 0.703 1.18 0.67,2.09 0.560 1.15 0.65,2.04 0.621
SIB on the first 24 months 0.72 0.38,1.34 0.297 0.95 0.49,1.84 0.877 0.95 0.48,1.85 0.871
Sex (M vs F) 1.64 0.93,2.90 0.087 1.60 0.90,2.84 0.109    
Age 1.02 1.00,1.04 0.119 1.02 1.00,1.04 0.124    
Stage III vs I-II 1.78 1.03,3.05 0.037 1.83 1.04,3.22 0.037    
G3 vs G2-G1 0.82 0.40,1.71 0.603 0.85 0.41,1.77 0.668    
OS SIB 1.15 0.61,2.17 0.674 1.71 0.86,3.40 0.127 1.51 0.77,2.98 0.235
Sex (M vs F) 2.64 1.38,5.07 0.003 2.77 1.43,5.37 0.003    
Age 1.03 1.00,1.06 0.043 1.03 1.00,1.06 0.031    
Stage III vs I-II 2.27 1.17,4.38 0.015 2.64 1.30,5.34 0.007    
G3 vs G2-G1 1.42 0.66,3.06 0.376 1.48 0.68,3.23 0.326    
CIC SIB 0.71 0.34,1.47 0.352 0.87 0.41,1.85 0.713 0.85 0.39,1.83 0.675
Sex (M vs F) 0.93 0.39,2.18 0.863 0.83 0.34,2.05 0.690    
Age 1.00 0.98,1.03 0.765 1.00 0.98,1.02 0.878    
Stage III vs I-II 2.09 0.99,4.38 0.052 2.13 0.97,4.70 0.061    
G3 vs G2-G1 0.44 0.13,1.48 0.184 0.43 0.13,1.45 0.173    
  1. Legend HR hazard ratio CI confidence interval, M vs F male vs female, UFS colostomy-free survival, OS Overall Survival, CIC Cumulative Incidence of colostomy