Table 1 Characteristics of 87 patients with locoregional recurrent esophageal cancer
Variables | Number | Percent |
|---|---|---|
Age (years) | ||
< 65 | 58 | 66.7 |
≥ 65 | 29 | 33.3 |
KPS | ||
70–80 | 32 | 36.8 |
>80 | 55 | 63.2 |
Gender | ||
Male | 65 | 74.7 |
Female | 22 | 25.3 |
Smoking | ||
Yes | 31 | 35.6 |
No | 56 | 64.4 |
Alcohol consumption | ||
Yes | 15 | 17.2 |
No | 72 | 82.8 |
Primary tumor location | ||
Upper thoracic | 34 | 39.1 |
Middle and lower thoracic | 53 | 60.9 |
Initial clinical stage | ||
I + II | 23 | 32.9 |
III | 47 | 67.1 |
Initial treatment | ||
Surgery + adjuvant radio(chemo)therapy | 11 | 12.6 |
Definitive chemoradiotherapy | 39 | 44.8 |
Definitive radiotherapy | 37 | 42.6 |
Pattern of recurrence | ||
Regional lymph node recurrence only | 14 | 16.1 |
Local failure | 62 | 71.3 |
Both | 11 | 12.6 |
Radiation dose in the initial treatment (Gy) | ||
≤ 50 | 12 | 13.8 |
> 50 | 75 | 86.2 |
Recurrence-free interval (months) | ||
≤ 12 | 38 | 43.7 |
> 12 | 49 | 56.3 |
Chemotherapy after recurrence | ||
Yes | 26 | 29.9 |
No | 61 | 70.1 |
Re-RT after recurrence | ||
Yes | 39 | 44.8 |
No | 48 | 55.2 |
Treatment moditily after recurrence | ||
Re-RT only | 20 | 23.0 |
CRT only | 7 | 8.0 |
Re-RT concomitant chemotherapy | 19 | 21.8 |
Best supportive care | 39 | 43.7 |
Salvage total esophagectomy | 3 | 3.4 |