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Table 3 Very hypo-fractionnated APBI discribed in the litterature

From: Single fraction of accelerated partial breast irradiation in the elderly: early clinical outcome

Authors

Year

# pts

MFU (months)

APBI techniques

Total dose (Gy)

D/f (Gy)

AG3 to (%)

LG3 tox (%)

LF (%)

RF (%)

DM (%)

Ex/good cosmetic result (%)

Sacchini

2008

18/34

31

HDRIORT

20/18

20/18

7.7

0

c

Khan

2013

30

11

Balloona

28

7 (BID)

0

0

Wilkinson

2012/17

45

74

Balloonb

28

7 (BID)

13.3

2

0

0

0

91

Showalter

2016

28

6

HDRIORT

12.5

12.5

0

93

Hannoun-Levi

2017

26

37

HDRMIB

16

16

7.6

0

0

0

88

Latorre

2018

20

24

HDRMIB

18

18

0

0

0

0

5

80

Present study

2018

48

40

HDRMIB

16

16

6.3

0

0

0

0

100

  1. aContura
  2. bMammosite
  3. cCosmetic results were better with 18 Gy compared to 20 Gy
  4. # Pts: number of patients; MFU: median follow-up; APBI: accelerated partial breast irradiation; HDRIORT: high-dose rate brachytherapy performed intraoperatively; MIB: multicatheter interstitial high-dose rate brachytherapy; D/f: dose per fraction; AG3 tox: acute ≥ Grade 3 toxicity; LG3 tox: late ≥ Grade 3 toxicity; LF: local failure; RF: regional failure; DM: distant metastasis; Ex/good cosmetic: percentages of excellent and good cosmetic results