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Table 1 Patients, lesions and treatment characteristics

From: Single fraction of accelerated partial breast irradiation in the elderly: early clinical outcome

Patient features Number of patients % / (min – max)
Patients included in SiFEBI trial
 Yes 26 54.2
 No 22 45.8
 Mean age (years) 77.7 (65.2–92.3)
ECOG-Performans Status
 0 41 85.5
 1 7 14.5
 Tumor side
 Left 28 54.9
 Right 23 45.1
Location
 Upper external quadrant 20 39.2
 Upper internal quadrant 5 9.8
 Lower internal quadrant 3 5.9
 Lower external quadrant 3 5.9
 Junction of external quadrant 6 11.8
 Junction of internal quadrant 3 5.9
 Junction of lower quadrant 3 5.9
 Junction of upper quadrant 6 11.7
 Periareolar 2 3.9
 Median tumor size (mm) 12 (3–32)
Tumor stage
 T1a 28 54.9
 T1b 18 35.3
 T1c 5 9.8
Axillary lymph node status
 N0 46 90.1
 N1mic 4 7.9
 N1 1 2.0
Histology type
 Invasive ductal carcinoma 44 86.3
 Invasive lobular carcinoma 3 5.9
 Other 4 7.8
Histological grade
 1 32 62.7
 2 14 27.4
 3 5 9.8
Hormonal status
 Positive 48 94.1
 Negative 3 5.9
 Her-2 status
 Over-expressed 5 9.8
 Non-over-expressed 46 90.2
Peri-neural invasion
 Yes 1 1.9
 No 50 98.1
 Median Ki-67 (%) 10 (5–60)
 Median surg. Marg.(mm) 5 (1–10)
Implant time
 Intra operative 47 92.2
 Post-operative 4 7.8
 Median time interv. Surg./APBI (d) 7 (1–63)
 Median number of vectors 11 (5–15)
 Median number of planes 2 (1–3)
 Median CTV (cc) 44 (11–124)
 Median V100% (%) 96 (86–100)
 Median V150% (%) 34 (23–48)
 Median V200% (%) 12 (8–21)
 Median DNR 0.35 (0.23–0.56)
  1. Median time interv. Surg./APBI: median time between intervention and sfAPBI; Median surg. Marg.: median surgical margins; DNR: dose non-homogeneity ratio = V100/V150