Skip to main content
Fig. 2 | Radiation Oncology

Fig. 2

From: Primary histiocytic sarcoma of the central nervous system: a case report with platelet derived growth factor receptor mutation and PD-L1/PD-L2 expression and literature review

Fig. 2

Final Pathological Examination. The H&E section show the diffuse proliferation of neoplastic histiocytes invading normal brain parenchyma (a × 10, upper normal brain; bottom neoplastic histiocytes); the neoplastic histiocytes show marked cytological atypia with brisk mitosis (b × 20). Immunohistochemical studies show the histiocytes positive for CD 163 (c ×10), CD68 (d × 10), CD45 and vimentin; negative for CD20, CD3, CD30, s-100, CD1a, CD21, CD23, pancytokeratin, MPO, CD61, CD123, GFAP, and BRAF. The neoplastic histiocytes are also positive for PD-L1 with both clones (e× 10, 22C3 and f× 10, 28–8)

Back to article page

Radiation Oncology

ISSN: 1748-717X

Contact us