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Table 3 Detailed results for the parallel organs. Statistical significance was tested for each parallel organ group in comparison with the planning system that achieved lowest averaged mean dose (bold). Any 0.01 ≤ p ≤ 0.05 is indicated with a *, and p ≤ 0.01 is indicated with **

From: Planning comparison of five automated treatment planning solutions for locally advanced head and neck cancer

  AIO AP RP1 RP2 RS
Mean ± SD Rank± SD Mean ± SD Rank ±SD Mean ± SD Rank ±SD Mean ± SD Rank ±SD Mean ± SD Rank ±SD
(Gy)   (Gy)   (Gy)   (Gy)   (Gy)  
OralCavity 36.1 ± 16.8 ** 2.56 ± 1.21 33.8 ± 17.8* 1.63 ± 0.62 34.1 ± 16.7** 1.81 ± 0.75 36.3 ± 16.2** 2.75 ± 1.34 31.3 ± 17.6 1.06 0.25
Parotid 21.9 ± 6.3 1.31 ± 0.6 21.2 ± 5.9 1.19 ± 0.40 21.6 ± 6.3 1.25 ± 0.45 22.8 ± 6.2 1.50 ± 0.73 21.4 ± 6.2 1.19 ± 0.54
Submand. Glands 35.2 ± 8.4 1.94 ± 1.34 33.6 ± 10.8 1.44 ± 0.81 38.2 ± 7.0 ** 2.88 ± 1.41 35.5 ± 9.3 1.88 ± 1.09 36.9 ± 7.6* 2.38 ± 1.15
UAT 38.8 ± 9.3 1.49 ± 0.37 39.3 ± 9.4 1.86 ± 0.64 43.4 ± 7.6** 2.99 ± 1.01 39.7 ± 8.9 1.89 ± 0.7 40.4 ± 8.4 2.00 ± 0.70
Average   1.83 ± 1.06*   1.53 ± 0.67   2.23 ± 1.20**   2.00 ± 1.08*   1.66 ± 0.91
  1. Abbreviations: AIO automatic interactive optimizer, AP auto-planning, RP RapidPlan, RS Raystation, SD standard deviation, UAT upper aerodigestve tract