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Table 2 Analysis on radiation dose and other factors affecting brainstem toxicities in Cox regression models

From: A retrospective dosimetry study of intensity-modulated radiotherapy for nasopharyngeal carcinoma: radiation-induced brainstem injury and dose-volume analysis

Factor p-value HR 95% CI for HR
T category(T4 vs T1–3) 0.029 5.94 1.2–29.43
GTVnx D2% 0.040 1.21 1.01–1.45
Dmax 0.003 1.15 1.05–1.26
D1% 0.003 1.16 1.05–1.28
D0.1cc 0.003 1.16 1.05–1.27
D1cc 0.006 1.15 1.04–1.27
  1. D 2% near the maximum absorbed dose of GTVnx, Dmax the maximum point dose of brainstem,
  2. D1% the dose of 1% brainstem volume, D0.1cc the maximum dose of brainstem delivered to a volume of 0.1 ml, D1cc the maximum dose of brainstem delivered to a volume of 1.0 ml, GTVnx
  3. Gross tumor volume of nasopharyngeal primary lesions and their direct extensions
  4. Abbreviation: HR hazard ratio, CI confidence interval, GTV Gross tumor volume
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