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Table 1 Patient’s features, RT prescriptions and response

From: Light and shadows of a new technique: is photon total-skin irradiation using helical IMRT feasible, less complex and as toxic as the electrons one?

  Patient #1 (female) Patient #2 (male) Patient #3 (male)
Diagnosis MF (stage IVA1; T4N0M0) with erithrodermic disease, Diffuse cutaneous and systemic localizations of cutaneous T cell lymphoma, Granulomatous MF (stage II) slack skin
Previous treatments Chemotherapy and UVB-PUVA, but never treated with radiotherapy Different types of cutaneous therapies (PUVA), chemotherapy and localized RT, and finally proposed for palliative total-skin irradiation Previously untreated
Prescribed dose (Median target dose) 27.0Gy/1.8Gy/fr
(upper body)
26.0Gy/2.0Gy/fr
(lower body)
(22.05Gy/1.47Gy/fr Gy for the scalp and eyelids) 23 days split in between the two
28.8Gy/1.8Gy/fr
(upper body)
28.8Gy/1.8Gy/fr
(lower body)
15 days split in between the two
30.4 Gy/1.9 Gy/fr
(upper body)
30.0 Gy/2 Gy/fr
(lower body)
8 days split in between the two
Compensative electrons boost on “under-dosed” regions One field electron boost (upper back) after the end of the photon treatment. 4 electron field boosts (right arm, left arm, inguinal, right foot dorsum).
During the split between the first and the second part of the photon treatment
9 electron field boosts (right and left forearm, right and left arm, right back, left back, internal right thigh).
During the split between the first and the second part of the photon treatment
Response to RT and duration Short complete remission (6 months) Short complete remission (6 months) Complete remission (4 years)