From: Hyperfractionated abdominal reirradiation for gastrointestinal malignancies
Characteristic | Median [IQR] or Number (%) |
---|---|
Age at 2nd Radiation Treatment (years) | 65 [54.1–69.1] |
Sex | |
 Male | 16 (67%) |
 Female | 8 (33%) |
Pathology of Initial Primary | |
 Pancreatic Adenocarcinoma | 11 (46%) |
 Upper GI Adenocarcinomaa | 4 (16.7%) |
 Colon Adenocarcinoma | 3 (12.5%) |
 Hepatobiliary Cancersb | 4 (16.7%) |
 Otherc | 2 (8.3%) |
Dose/fractionation of 1st Radiation Treatment (total dose in Gray (Gy)/total number of fractions) | |
 30Gy/24 fractions | 1 (4.2%) |
 30Gy/10 fractions | 4 (16.7%) |
 30Gy/12 fractions | 1 (4.2%) |
 35Gy/14 fractions | 2 (8.3%) |
 45Gy/25 fractions | 8 (33.3%) |
 50.4Gy/28 fractions | 8 (33.3%) |
Retreatment Interval (months) | 27.9 [18.6–38.9] |
Type of Post-1st Radiation Disease | |
 Recurrent Disease | 21 (87.5%) |
 Second Primary Tumor | 3 (12.5%) |
Location of Post-1st Radiation Disease | |
 Pancreas | 14 (58.3%) |
 Stomach/Duodenum | 5 (20.8%) |
 Liver | 2 (8.3%) |
 Otherd | 3 (12.5%) |
Reirradiation Intent | |
 Definitive/Local Control | 16 (67%) |
 Palliation of Bleeding | 5 (20.8%) |
 Palliation of Pain | 2 (8.3%) |
 Palliation of Tumor Thrombus | 1 (4.2%) |
Reirradiation Dosee (total dose in Gray (Gy)/total number of fractions) | |
 15Gy/10 fractions | 1 (4.2%) |
 30Gy/20 fractions | 7 (29.2%) |
 39Gy/26 fractions | 15 (58.3%) |
 45Gy/30 fractions | 1 (4.2%) |
Reirradiation Technique | |
 3D Conformal | 15 (62.5%) |
 Intensity-modulated radiation therapy | 9 (37.5%) |
Concurrent Chemotherapy | |
 Yes | 17 (70.9%) |
 No | 7 (29.2%) |