Radiosurgery or hypofractionated stereotactic radiotherapy for brain metastases from radioresistant primaries (melanoma and renal cancer)

Table 4 Univariate and Multivariate analysis of covariates influencing local control

	Univariate analysis			Multivariate analysis^a
	HR	CI 95%	p-value	HR	CI 95%	p-value
Time from MRI to first irradiation (ref < 14 days)	3.60	[1.27;10.19]	0.009	3.98	[1.40;11.27]	0.003
GTV (ref < 530)	2.44	[1.24;4.80]	0.007	2.30	[1.16;4.55]	0.014
Coverage Index (ref < 0.985)	0.43	[0.21;0.89]	0.019	0.46	[0.22;0.95]	0.029

ISSN: 1748-717X