Table 3 Patient, treatment and volume characteristics in patients with and without unacceptable deviation (UD)
Variable | Patients without UD (n = 18) | Patient with UD (n = 4) | p-value* |
|---|---|---|---|
Gender | |||
 Female | 4/18 (22%) | 1/4 (25%) | 1.000 |
 Male | 14/18 (78%) | 3/4 (75%) | 1.000 |
Median age at randomization (range) | 68 (37–88) | 48 (27–73) | 0.121 |
Surgery | |||
 No | 6/18 (33%) | 2/4 (50%) | 0.602 |
 Yes | 12/18 (67%) | 2/4 (50%) |  |
Number of lesions treated by surgery | |||
 1 | 11/12 (92%) | 1/2 (50%) |  |
 2 | 1/12 (8%) | 1/2 (50%) | |
SRS | |||
 No | 10/18 (56%) | 2/4 (50%) | 1.000 |
 Yes | 8/18 (44%) | 2/4 (50%) | 1.000 |
Number of lesions treated by SRS | |||
 1 | 6/8 (75%) | 1/2 (50%) |  |
 2 | 2/8 (25%) | 1/2 (50%) | |
Simultaneous Integrated Boost | |||
 No | 13/18 (72%) | 3/4 (75%) | 1.000 |
 Yes | 5/18 (28%) | 1/4 (25%) |  |
Number of SIB treatment | |||
 1 | 2/5 (40%) | 1/1 (100%) |  |
 2 | 2/5 (40%) | 0 | |
 3 | 1/5 (20%) | 0 |  |
Right hippocampus: | |||
 Volume (cm3) | 2.0 (0.9–3.9) | 3.8 (2.1–5.7) | 0.052 |
 Avoidance Volume (cm3) | 13.6 (6.8–20.7) | 17.0 (15.4–27.9) | 0.080 |
Left hippocampus: | |||
 Volume (cm3) | 1.9 (1.0–3.3) | 4.1 (2.4–4.5) | 0.004 |
 Avoidance Volume (cm3) | 13.3 (6.7–20.3) | 17.5 (15.3–21.5) | 0.035 |
Both hippocampi: | |||
 Volume (cm3) | 4.0 (2.3–7.2) | 7.9 (4.5–10.0) | 0.013 |
 Avoidance volume (cm3) | 26.7 (13.5–41.0) | 34.0 (31.7–49.4) | 0.061 |