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Table 1 Study population

From: RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue

Demographics

N

N

Cases

Experiment

Validation

25

1122

Gender

 ▪ Men

19

670

 ▪ Women

6

452

Smoking status

 ▪ Active smokers

10

164

 ▪ Ex-smokers

14

437

 ▪ Never-smoker

1

N/A

Histology

 ▪ Non-malignant lung

25

108

 ▪ Squamous ca.

11

501

 ▪ Adenoca.

14

513

COPD status

 ▪ FEV1 / FEV < 70%

15

74

 ▪ FEV1 / FEV > 70%

10

146

CRP level

 ▪ CRP < 5 mg/L

14

N/A

 ▪ CRP > 5 mg/L

11

N/A

Disease stage (TNM 7)

 ▪ Stage I

15

575

 ▪ Stage II

6

322

 ▪ Stage III

3

189

 ▪ Stage IV

1

36

  1. Characteristics of the study population. Ex-smoking was defined as a total smoking cessation for at least four weeks before the biopsy