Table 2 Frequency of adverse event by recommended dose category
Bladder total EQD2 D2cc | All | |||||||
|---|---|---|---|---|---|---|---|---|
0 to 80 | 80 to 90 | > 90 | ||||||
n | % | n | % | n | % | n | % | |
GU Toxicity Grade | 24 | 85.7 | 5 | 62.5 | 14 | 70.0 | 43 | 76.8 |
0 | ||||||||
1 | 2 | 7.1 | 1 | 12.5 | 1 | 5.0 | 4 | 7.1 |
2 | 1 | 3.6 | 1 | 12.5 | 3 | 15.0 | 5 | 8.9 |
3 | 0 | 0.0 | 1 | 12.5 | 2 | 10.0 | 3 | 5.4 |
4 | 1 | 3.6 | 0 | 0.0 | 0 | 0.0 | 1 | 1.8 |
All | 28 | 100.0 | 8 | 100.0 | 20 | 100.0 | 56 | 100.0 |
Rectal total EQD2 D2cc | All | |||||||
0 to 65 | 65 to 75 | > 75 | ||||||
n | % | n | % | n | % | n | % | |
GI Toxicity Grade | 8 | 72.7 | 17 | 85.0 | 16 | 64.0 | 41 | 73.2 |
0 | ||||||||
1 | 0 | 0.0 | 0 | 0.0 | 4 | 16.0 | 4 | 7.1 |
2 | 1 | 9.1 | 0 | 0.0 | 2 | 8.0 | 3 | 5.4 |
3 | 1 | 9.1 | 3 | 15.0 | 3 | 12.0 | 7 | 12.5 |
4 | 1 | 9.1 | 0 | 0.0 | 0 | 0.0 | 1 | 1.8 |
All | 11 | 100.0 | 20 | 100.0 | 25 | 100.0 | 56 | 100.0 |
Sigmoid total EQD2 D2cc | All | |||||||
0 to 65 | 65 to 75 | > 75 | ||||||
n | % | n | % | n | % | n | % | |
GI Toxicity Grade | 20 | 90.9 | 11 | 57.9 | 10 | 66.7 | 41 | 73.2 |
0 | ||||||||
1 | 1 | 4.5 | 1 | 5.3 | 2 | 13.3 | 4 | 7.1 |
2 | 0 | 0.0 | 2 | 10.5 | 1 | 6.7 | 3 | 5.4 |
3 | 1 | 4.5 | 5 | 26.3 | 1 | 6.7 | 7 | 12.5 |
4 | 0 | 0.0 | 0 | 0.0 | 1 | 6.7 | 1 | 1.8 |
All | 22 | 100.0 | 19 | 100.0 | 15 | 100.0 | 56 | 100.0 |