Table 2 Characteristics of three patients with grade ≥ 3 acute radiation pneumonitis
Factors | Patients | |||
|---|---|---|---|---|
Radiation pneumonitis grade | 3 | 4 | 4 | |
Sex | Male | Male | Male | |
Age (year) | 88 | 79 | 80 | |
ECOG performance status | 2 | 1 | 1 | |
Pre-treatment pulmonary function test | FVC (L) | 2.5 | 2.1 | 4.8 |
FEV1 (L) | 1.9 | 2.0 | 2.9 | |
DLco (%) | 85 | 37 | 84 | |
Combined pulmonary disease | None | IIP | None | |
Aim | Definitive | Salvage | Salvage | |
SBRT dose (Gy/fraction) | 48/4 | 40/4 | 60/4 | |
CRT dose (Gy/fraction) | 66/33 | 60/10 | 60/30 | |
GTV (cc) | Lung | 29.2 | 6.1 | 6.4 |
Nodal area | 17.7 | 4.9 | 24.2 | |
PTV (cc) | Lung | 89.6 | 26.5 | 30.1 |
Nodal area | 298.2 | 27.7 | 361.0 | |
Chemotherapy | None | None | None | |
Occurrence time of radiation pneumonitis (days) | 40 | 43 | 18 | |
Bilateral or unilateral lung involvement of radiation pneumonitis | Unilateral | Bilateral | Bilateral | |
Time from onset of symptoms to death (days) | 53 | 17 | 15 | |