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Table 2 Dose comparisons among plans generated from IMRT with FB, T-DIBH and A-DIBH

From: Abdominal DIBH reduces the cardiac dose even further: a prospective analysis

 

IMRT plans

P value

Parameters

FB_IMRT

T-DIBH_IMRT

A-DIBH_IMRT

FB vs. T

FB vs. A

T vs. A

PTV

 Mean (Gy)

49.43±0.33

49.37±0.47

49.33±0.49

N.S.

N.S.

N.S.

 D2% (Gy)

51.46±0.61

51.29±0.61

51.16±0.57

N.S.

N.S.

N.S.

 V105% (%)

0.37±0.56

0.36±0.97

0.14±0.43

N.S.

N.S.

N.S.

 HI (%)

10.26±1.69

9.83±1.53

9.32±1.34

N.S.

N.S.

N.S.

Heart

 Mean (Gy)

1.96±2.25

1.37±0.44

1.18±0.26

***

***

***

 D2% (Gy)

14.67±5.29

7.62±5.29

5.61±3.03

***

***

***

 V5 (%)

6.58±3.25

2.83±2.54

1.80±1.46

***

***

***

 V10 (%)

4.01±2.32

1.32±1.60

0.68±0.84

***

***

***

 V20 (%)

0.59±0.49

0.16±0.29

0.05±0.11

***

***

***

 V30 (%)

0.07±0.09

0.01±0.04

0.00±0.00

**

**

N.S.

LADCA

 Mean (Gy)

16.10±7.45

8.60±6.60

7.35±5.42

***

***

**

 D2% (Gy)

25.07±11.02

14.24±9.43

13.11±9.51

***

***

*

 V5 (%)

83.67±28.38

49.75±39.71

43.99±38.93

***

***

**

 V10 (%)

68.36±35.95

30.44±38.59

25.66±32.84

***

***

*

 V20 (%)

36.27±31.19

10.77±23.47

5.69±14.18

***

***

*

 V30 (%)

6.66±15.42

0.76±2.89

1.00±4.07

**

**

N.S.

Left lung

 Mean (Gy)

5.90±2.24

5.65±1.58

5.62±1.05

N.S.

N.S.

N.S.

 D2% (Gy)

37.46±5.31

39.12±2.67

38.34±2.93

N.S.

N.S.

N.S.

 V5 (%)

22.84±7.01

23.53±4.48

22.82±3.79

N.S.

N.S.

N.S.

 V10 (%)

15.95±6.21

15.40±3.67

14.49±3.21

N.S.

N.S.

*

 V20 (%)

11.12±5.55

10.67±3.39

9.83±3.01

N.S.

N.S.

*

 V30 (%)

6.52±4.59

6.6±2.90

5.97±2.60

N.S.

N.S.

N.S.

  1. Note: * <0.05, ** <0.01,*** <0.001, N.S.: not significant