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Table 5 Univariate analysis for risk factors of ≥grade 1 late morbidities in bladder

From: Dose constraints in the rectum and bladder following carbon-ion radiotherapy for uterus carcinoma: a retrospective pooled analysis

 

24 fractions, n = 41

20 fractions, n = 91

Factors

Subgroup

Number of patients

p value

Subgroup

Number of patients

p value

V10

≥79.8 cm3

21

0.698

≥154.5 cm3

46

0.194

< 79.8 cm3

20

< 154.5 cm3

45

V20

≥76.7 cm3

20

0.687

≥121.1 cm3

45

0.562

< 76.7 cm3

21

< 121.1 cm3

46

V30

≥56.5 cm3

21

0.790

≥93.9 cm3

46

0.790

< 56.5 cm3

20

< 93.9 cm3

45

V40

≥48.5 cm3

21

0.757

≥61.2 cm3

45

0.281

< 48.5 cm3

20

< 61.2 cm3

46

V50

≥32.5 cm3

21

0.574

≥32.0 cm3

46

0.243

< 32.5 cm3

20

< 32.0 cm3

45

V60

≥20.1 cm3

15

0.845

≥11.5 cm3

44

0.054

< 20.1 cm3

15

< 11.5 cm3

44

D5cc

≥63.7 Gy (RBE)

21

0.487

≥63.8 Gy (RBE)

46

0.011

< 63.7 Gy (RBE)

20

< 63.8 Gy (RBE)

45

D2cc

≥66.8 Gy (RBE)

21

0.487

≥65.8 Gy (RBE)

46

0.288

< 66.8 Gy (RBE)

20

< 65.8 Gy (RBE)

45

Dmax

≥71.0 Gy (RBE)

21

0.057

≥71.0 Gy (RBE)

48

0.631

< 71.0 Gy (RBE)

20

< 71.0 Gy (RBE)

43

Diabetes

Yes

2

0.543

Yes

7

0.003

No

39

No

84

Anticoagulants

Yes

1

0.603

Yes

10

0.812

No

40

No

81

Age

≥56 years

21

0.489

≥60 years

47

0.519

< 56 years

20

< 60 years

44

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Radiation Oncology

ISSN: 1748-717X

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