Table 3 Correlation between dose-volume histogram parameters and ≥ grade 1 late morbidities in rectum and bladder

Rectum

n = 18

n = 23

n = 66

n = 25

 V10 (mean ± SD, cc)

36.0 ± 22.9

46.7 ± 26.0

0.118

32.8 ± 11.6

26.3 ± 10.5

0.096

 V20 (mean ± SD, cc)

34.2 ± 22.5

45.8 ± 25.8

0.153

28.1 ± 10.6

26.0 ± 10.1

0.397

 V30 (mean ± SD, cc)

29.1 ± 21.1

34.9 ± 18.4

0.365

19.8 ± 9.4

20.4 ± 9.3

0.807

 V40 (mean ± SD, cc)

20.5 ± 16.0

24.7 ± 15.9

0.421

12.6 ± 8.5

14.7 ± 8.6

0.294

 V50 (mean ± SD, cc)

11.3 ± 11.0

15.5 ± 11.7

0.255

6.3 ± 6.2

8.4 ± 5.8

0.156

 V60 (mean ± SD, cc)

5.1 ± 9.1

7.7 ± 7.7

0.332

1.2 ± 2.1

1.8 ± 2.0

0.262

 D5 cc [mean ± SD, Gy (RBE)]

54.7 ± 7.4

57.1 ± 8.5

0.349

48.1 ± 8.3

52.1 ± 6.2

0.017

 D2 cc [mean ± SD, Gy (RBE)]

59.1 ± 7.0

61.7 ± 6.8

0.242

53.7 ± 6.8

57.3 ± 5.3

0.011

 Dmax [mean ± SD, Gy (RBE)]

65.0 ± 7.2

67.0 ± 6.4

0.360

66.7 ± 4.7

68.3 ± 4.6

0.160

Bladder

n = 36

n = 5

n = 74

n = 17

 V10 (mean ± SD, cc)

104.4 ± 78.4

108.0 ± 94.0

0.928

150.3 ± 67.6

135.3 ± 63.9

0.410

 V20 (mean ± SD, cc)

98.3 ± 74.8

91.8 ± 61.8

0.858

124.1 ± 59.7

121.6 ± 59.4

0.876

 V30 (mean ± SD, cc)

71.0 ± 45.9

67.9 ± 43.4

0.890

98.3 ± 52.4

101.9 ± 57.0

0.808

 V40 (mean ± SD, cc)

55.9 ± 37.3

53.5 ± 38.8

0.897

64.2 ± 36.2

76.0 ± 48.8

0.265

 V50 (mean ± SD, cc)

38.3 ± 27.9

38.5 ± 30.3

0.988

34.9 ± 24.2

48.0 ± 30.4

0.061

 V60 (mean ± SD, cc)

25.5 ± 22.5

20.4 ± 15.0

0.638

13.3 ± 11.7

18.8 ± 13.7

0.097

 D5 cc [mean ± SD, Gy (RBE)]

62.9 ± 7.8

65.0 ± 7.4

0.577

61.9 ± 7.3

64.8 ± 6.4

0.041

 D2 cc [mean ± SD, Gy (RBE)]

65.3 ± 6.9

66.2 ± 7.8

0.819

64.9 ± 6.4

66.9 ± 5.8

0.117

 Dmax [mean ± SD, Gy (RBE)]

67.8 ± 7.8

69.4 ± 8.2

0.688

70.1 ± 4.8

70.4 ± 4.2

0.774